A machine learning model trained on a high-throughput antibacterial screen increases the hit rate of drug discovery.

Rahman ASMZ, Liu C, Sturm H, Hogan AM, Davis R, Hu P, Cardona ST

PLoS computational biology, 2022

doi:10.1371/journal.pcbi.1010613.

Gradients in gene essentiality reshape antibacterial research.

Hogan AM, Cardona ST

FEMS microbiology reviews, 2022

doi:10.1093/femsre/fuac005.

Deep learning-driven prediction of drug mechanism of action from large-scale chemical-genetic interaction profiles.

Liu C, Hogan AM, Sturm H, Khan MW, Islam MM, Rahman ASMZ, Davis R, Cardona ST, Hu P

Journal of cheminformatics, 2022

doi:10.1186/s13321-022-00596-6.

New auranofin analogs with antibacterial properties against Burkholderia clinical isolates.

Maydaniuk D, Wu B, Truong D, Liyanage SH, Hogan AM, Yap ZL, Yan M, Cardona ST

Antibiotics (Basel), 2021

doi:10.3390/antibiotics10121443.

Improved Dynamic Range of a Rhamnose-Inducible Promoter for Gene Expression in Burkholderia spp.

Hogan AM, Jeffers KR, Palacios A, Cardona ST

Applied and environmental microbiology, 2021

doi:10.1128/AEM.00647-21.

A Broad-Host-Range CRISPRi Toolkit for Silencing Gene Expression in Burkholderia.

Hogan AM, Rahman ASMZ, Lightly TJ, Cardona ST

ACS synthetic biology, 2019

doi:10.1021/acssynbio.9b00232.

The Effect of 2-thiocyanatopyridine derivative 11026103 on Burkholderia Cenocepacia: resistance mechanisms and systemic impact.

Nunvar J, Hogan AM, Buroni S, Savina S, Makarov V, Cardona ST, Drevinek P

Antibiotics (Basel, Switzerland), 2019

doi:10.3390/antibiotics8040159.

Synthesis and antibiotic activity of novel acylated phloroglucinol compounds against methicillin-resistant Staphylococcus aureus.

Mittal N, Tesfu HH, Hogan AM, Cardona ST, Sorensen JL

The Journal of antibiotics, 2019

doi:10.1038/s41429-019-0153-4.

Competitive fitness of essential gene knockdowns reveals a broad-spectrum antibacterial inhibitor of the cell division protein FtsZ.

Hogan AM, Scoffone VC, Makarov V, Gislason AS, Tesfu H, Stietz MS, Brassinga AKC, Domaratzki M, Li X, Azzalin A, Biggiogera M, Riabova O, Monakhova N, Chiarelli LR, Riccardi G, Buroni S, Cardona ST

Antimicrobial agents and chemotherapy, 2018

doi:10.1128/AAC.01231-18.

Essential two-component systems regulating cell envelope functions: opportunities for novel antibiotic therapies.

Cardona ST, Choy M, Hogan AM

The Journal of membrane biology, 2018

doi:10.1007/s00232-017-9995-5.

CD24 induces changes to the surface receptors of B cell microvesicles with variable effects on their RNA and protein cargo.

Ayre DC, Chute IC, Joy AP, Barnett DA, Hogan AM, Grüll MP, Peña-Castillo L, Lang AS, Lewis SM, Christian SL

Scientific reports, 2017

doi:10.1038/s41598-017-08094-8.

Nile red and 2-NBDG are incompatible for the simultaneous detection of lipid and glucose accumulation.

Hogan AM, Swaninathan V, Pallegar NK, Christian SL

International Journal of Spectroscopy, 2016

doi:10.1155/2016/5215086.

Dynamic regulation of CD24 expression and release of CD24-containing microvesicles in immature B cells in response to CD24 engagement.

Ayre DC, Elstner M, Smith NC, Moores ES, Hogan AM, Christian SL

Immunology, 2015

doi:10.1111/imm.12493.