Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure.

Neniskyte U, Kuliesiute U, Vadisiute A, Jevdokimenko K, Coletta L, Deivasigamani S, Pamedytyte D, Daugelaviciene N, Dabkeviciene D, Perlas E, Bali A, Basilico B, Gozzi A, Ragozzino D, Gross CT

The EMBO journal, 2023

doi:10.15252/embj.2022111790.

MiR-142-3p is a critical modulator of TNF-mediated neuronal toxicity in multiple sclerosis.

De Vito F, Balletta S, Caioli S, Musella A, Guadalupi L, Vanni V, Fresegna D, Bassi MS, Gilio L, Sanna K, Gentile A, Bruno A, Dolcetti E, Buttari F, Pavone L, Furlan R, Finardi A, Perlas E, Hornstein E, Centonze D, Mandolesi G

Current neuropharmacology, 2023

doi:10.2174/1570159x21666230404103914.

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.

Taliani V, Buonaiuto G, Desideri F, Setti A, Santini T, Galfrè S, Schirone L, Mariani D, Frati G, Valenti V, Sciarretta S, Perlas E, Nicoletti C, Musarò A, Ballarino M

eLife, 2023

doi:10.7554/eLife.81360.

Induction of flight via midbrain projections to the cuneiform nucleus.

Tsang E, Orlandini C, Sureka R, Crevenna AH, Perlas E, Prankerd I, Masferrer ME, Gross CT

PloS one, 2023

doi:10.1371/journal.pone.0281464.

Deletion of LBR N-terminal domains recapitulates Pelger-Huet anomaly phenotypes in mouse without disrupting X chromosome inactivation.

Young AN, Perlas E, Ruiz-Blanes N, Hierholzer A, Pomella N, Martin-Martin B, Liverziani A, Jachowicz JW, Giannakouros T, Cerase A

Communications biology, 2021

doi:10.1038/s42003-021-01944-2.

Correction to: MicroRNA-34 contributes to the stress-related behavior and affects 5-HT prefrontal/GABA amygdalar system through regulation of corticotropin-releasing factor receptor 1.

Andolina D, Di Segni M, Accoto A, Lo Iacono L, Borreca A, Ielpo D, Berretta N, Perlas E, Puglisi-Allegra S, Ventura R

Molecular neurobiology, 2019

doi:10.1007/s12035-019-01848-7.

Nerve growth factor-mediated photoablation of nociceptors reduces pain behavior in mice.

Nocchi L, Portulano C, Franciosa F, Doleschall B, Panea M, Roy N, Maffei M, Gargano A, Perlas E, Heppenstall PA

Pain, 2019

doi:10.1097/j.pain.0000000000001620.

MicroRNA-34 contributes to the stress-related behavior and affects 5-HT prefrontal/GABA amygdalar system through regulation of corticotropin-releasing factor receptor 1.

Andolina D, Di Segni M, Accoto A, Lo Iacono L, Borreca A, Ielpo D, Berretta N, Perlas E, Puglisi-Allegra S, Ventura R

Molecular neurobiology, 2018

doi:10.1007/s12035-018-0925-z.

miR-135a Regulates Synaptic Transmission and Anxiety-Like Behavior in Amygdala.

Mannironi C, Biundo A, Rajendran S, De Vito F, Saba L, Caioli S, Zona C, Ciotti T, Caristi S, Perlas E, Del Vecchio G, Bozzoni I, Rinaldi A, Mele A, Presutti C

Molecular neurobiology, 2018

doi:10.1007/s12035-017-0564-9.

Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons.

Dhandapani R, Arokiaraj CM, Taberner FJ, Pacifico P, Raja S, Nocchi L, Portulano C, Franciosa F, Maffei M, Hussain AF, de Castro Reis F, Reymond L, Perlas E, Garcovich S, Barth S, Lechner SG, Johnsson K, Heppenstall PA

Nature communications, 2018

doi:10.1038/s41467-018-04049-3.

MicroRNA degradation by a conserved target RNA regulates animal behavior.

Bitetti A, Mallory AC, Golini E, Carrieri C, Carreño Gutiérrez H, Perlas E, Pérez-Rico YA, Tocchini-Valentini GP, Enright AJ, Norton WHJ, Mandillo S, O'Carroll D, Shkumatava A

Nature structural & molecular biology, 2018

doi:10.1038/s41594-018-0032-x.

miR-142-3p is a key regulator of IL-1β-dependent synaptopathy in neuroinflammation.

Mandolesi G, De Vito F, Musella A, Gentile A, Bullitta S, Fresegna D, Sepman H, Di Sanza C, Haji N, Mori F, Buttari F, Perlas E, Teresa Ciotti M, Hornstein E, Bozzoni I, Presutti C, Centonze D

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016

doi:10.1523/JNEUROSCI.0851-16.2016.

miR-142-3p Is a Key Regulator of IL-1 beta-Dependent Synaptopathy in Neuroinflammation

Mandolesi G, De Vito F, Musella A, Gentile A, Bullitta S, Fresegna D, Sepman H, Di Sanza C, Haji N, Mori F, Buttari F, Perlas E, Ciotti MT, Hornstein E, Bozzoni I, Presutti C, Centonze D

JOURNAL OF NEUROSCIENCE, 2017

doi:10.1523/JNEUROSCI.0851-16.2016.

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems.

Guidi A, Lalli C, Perlas E, Bolasco G, Nibbio M, Monteagudo E, Bresciani A, Ruberti G

PLoS neglected tropical diseases, 2016

doi:10.1371/journal.pntd.0004928.

TMEM16F Regulates Spinal Microglial Function in Neuropathic Pain States.

Batti L, Sundukova M, Murana E, Pimpinella S, De Castro Reis F, Pagani F, Wang H, Pellegrino E, Perlas E, Di Angelantonio S, Ragozzino D, Heppenstall PA

Cell reports, 2016

doi:10.1016/j.celrep.2016.05.039.

A subpopulation of itch-sensing neurons marked by Ret and somatostatin expression.

Stantcheva KK, Iovino L, Dhandapani R, Martinez C, Castaldi L, Nocchi L, Perlas E, Portulano C, Pesaresi M, Shirlekar KS, de Castro Reis F, Paparountas T, Bilbao D, Heppenstall PA

EMBO reports, 2016

doi:10.15252/embr.201540983.

Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci.

Comazzetto S, Di Giacomo M, Rasmussen KD, Much C, Azzi C, Perlas E, Morgan M, O'Carroll D

PLoS genetics, 2014

doi:10.1371/journal.pgen.1004597.

Modulation of social behavior by the agouti pigmentation gene

Carola V, Perlas E, Zonfrillo F, Soini HA, Novotny MV, Gross CT

Frontiers in Behavioral Neuroscience, 2014

doi:10.3389/fnbeh.2014.00259.

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance

Gurniak CB, Chevessier F, Jokwitz M, Jönsson F, Perlas E, Richter H, Matern G, Boyl PP, Chaponnier C, Fürst D, Schröder R, Witke W

European journal of cell biology, 2014

doi:10.1016/j.ejcb.2014.01.007.

Tubulin acetyltransferase αTAT1 destabilizes microtubules independently of its acetylation activity

Kalebic N, Martinez C, Perlas E, Hublitz P, Bilbao-Cortes D, Fiedorczuk K, Andolfo A, Heppenstall PA

Molecular and cellular biology, 2013

doi:10.1128/mcb.01044-12.

αTAT1 is the major α-tubulin acetyltransferase in mice

Kalebic N, Sorrentino S, Perlas E, Bolasco G, Martinez C, Heppenstall PA

Nature communications, 2013

doi:10.1038/ncomms2962.

E-peptides control bioavailability of IGF-1

Hede MS, Salimova E, Piszczek A, Perlas E, Winn N, Nastasi T, Rosenthal N

PloS one, 2012

doi:10.1371/journal.pone.0051152.

Generation and characterization of an Advillin-Cre driver mouse line

Zurborg S, Piszczek A, Martínez C, Hublitz P, Al Banchaabouchi M, Moreira P, Perlas E, Heppenstall PA

Molecular pain, 2011

doi:10.1186/1744-8069-7-66.

The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling

Suljagic M, Longo PG, Bennardo S, Perlas E, Leone G, Laurenti L, Efremov DG

Blood, 2010

doi:10.1182/blood-2010-03-275180.

N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex

Bellenchi GC, Gurniak CB, Perlas E, Middei S, Ammassari-Teule M, Witke W

Genes & development, 2007

doi:10.1101/gad.434307.

ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program

Pelosi M, Marampon F, Zani BM, Prudente S, Perlas E, Caputo V, Cianetti L, Berno V, Narumiya S, Kang SW, Musarò A, Rosenthal N

Molecular and cellular biology, 2007

doi:10.1128/mcb.01735-06.

Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behavior

Pilo Boyl P, Di Nardo A, Mulle C, Sassoè-Pognetto M, Panzanelli P, Mele A, Kneussel M, Costantini V, Perlas E, Massimi M, Vara H, Giustetto M, Witke W

The EMBO journal, 2007

doi:10.1038/sj.emboj.7601737.

Identification of novel peptide hormones in the human proteome by hidden Markov model screening

Mirabeau O, Perlas E, Severini C, Audero E, Gascuel O, Possenti R, Birney E, Rosenthal N, Gross C

Genome research, 2007

doi:10.1101/gr.5755407.

The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration

Gurniak CB, Perlas E, Witke W

Developmental biology, 2005

doi:10.1016/j.ydbio.2004.11.010.