Abalone peptide increases stress resilience and cost-free longevity via SKN-1-governed transcriptional metabolic reprogramming in C. elegans.

Sarkans U, Madhusoodanan N, Mushtaq A, Petrov A, Griffiths-Jones S, Ontiveros-Palacios N, Nawrocki E, Griss J, Meldal B, Bowler-Barnett E, Paysan-Lafosse T, Armstrong D, Manners E, Hunter F, Cornu H, O’Donovan C, Harrus D, Zaru R, Pearce M, Eduardo Ribas C, Sweeney B, Swan A, Mishra A.

2021

doi:10.6019/tol.guidewebinarseries-t.2021.00001.1.

Sea Cucumber-Derived Peptides Alleviate Oxidative Stress in Neuroblastoma Cells and Improve Survival in <i>C. elegans</i> Exposed to Neurotoxic Paraquat.

Lu M, Mishra A, Boschetti C, Lin J, Liu Y, Huang H, Kaminski CF, Huang Z, Tunnacliffe A, Kaminski Schierle GS.

Oxid Med Cell Longev, 2021

doi:10.1155/2021/8842926.

Human epidermal stem cell differentiation is modulated by specific lipid subspecies.

Vietri Rudan M, Mishra A, Klose C, Eggert US, Watt FM.

Proc Natl Acad Sci U S A, 2020

doi:10.1073/pnas.2011310117.

Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies.

Lautenschläger J, Wagner-Valladolid S, Stephens AD, Fernández-Villegas A, Hockings C, Mishra A, Manton JD, Fantham MJ, Lu M, Rees EJ, Kaminski CF, Kaminski Schierle GS.

J Biol Chem, 2020

doi:10.1074/jbc.ra119.011650.

Design of a Functionalized Metal-Organic Framework System for Enhanced Targeted Delivery to Mitochondria.

Haddad S, Abánades Lázaro I, Fantham M, Mishra A, Silvestre-Albero J, Osterrieth JWM, Kaminski Schierle GS, Kaminski CF, Forgan RS, Fairen-Jimenez D.

J Am Chem Soc, 2020

doi:10.1021/jacs.0c00188.

Structural progression of amyloid-β Arctic mutant aggregation in cells revealed by multiparametric imaging.

Lu M, Williamson N, Mishra A, Michel CH, Kaminski CF, Tunnacliffe A, Kaminski Schierle GS.

J Biol Chem, 2019

doi:10.1074/jbc.ra118.004511.

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.

Liakath-Ali K, Mills EW, Sequeira I, Lichtenberger BM, Pisco AO, Sipilä KH, Mishra A, Yoshikawa H, Wu CC, Ly T, Lamond AI, Adham IM, Green R, Watt FM.

Nature, 2018

doi:10.1038/s41586-018-0032-3.

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis.

Mishra A, Oulès B, Pisco AO, Ly T, Liakath-Ali K, Walko G, Viswanathan P, Tihy M, Nijjher J, Dunn SJ, Lamond AI, Watt FM.

Elife, 2017

doi:10.7554/elife.27356.

10th Anniversary Treasure Hunt

Armstrong D, Burke M, Huerta L, Levchenko M, Mitchell A, Morgan S, Mugumbate G, Mutowo P, Orchard S, Perry E, Pundir S, Richardson L, Tang A.

2017

doi:10.6019/tol.treasure-t.2017.00001.1.

A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.

Walko G, Woodhouse S, Pisco AO, Rognoni E, Liakath-Ali K, Lichtenberger BM, Mishra A, Telerman SB, Viswanathan P, Logtenberg M, Renz LM, Donati G, Quist SR, Watt FM.

Nat Commun, 2017

doi:10.1038/ncomms14744.

Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.

Hayes TF, Benaich N, Goldie SJ, Sipilä K, Ames-Draycott A, Cai W, Yin G, Watt FM.

Cancer Lett, 2016

doi:10.1016/j.canlet.2016.09.014.

Rewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis.

Benaich N, Woodhouse S, Goldie SJ, Mishra A, Quist SR, Watt FM.

Cell Rep, 2014

doi:10.1016/j.celrep.2014.08.062.

Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation.

Connelly JT, Mishra A, Gautrot JE, Watt FM.

PLoS One, 2011

doi:10.1371/journal.pone.0027259.

ATP hydrolysis is required for relocating cohesin from sites occupied by its Scc2/4 loading complex.

Hu B, Itoh T, Mishra A, Katoh Y, Chan KL, Upcher W, Godlee C, Godlee C, Roig MB, Shirahige K, Nasmyth K.

Curr Biol, 2011

doi:10.1016/j.cub.2010.12.004.

A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion.

Kurze A, Michie KA, Dixon SE, Mishra A, Itoh T, Khalid S, Strmecki L, Shirahige K, Haering CH, Löwe J, Nasmyth K.

EMBO J, 2011

doi:10.1038/emboj.2010.315.

Both interaction surfaces within cohesin's hinge domain are essential for its stable chromosomal association.

Mishra A, Hu B, Kurze A, Beckouët F, Farcas AM, Dixon SE, Katou Y, Khalid S, Shirahige K, Nasmyth K.

Curr Biol, 2010

doi:10.1016/j.cub.2009.12.059.

Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity.

Rowland BD, Roig MB, Nishino T, Kurze A, Uluocak P, Mishra A, Beckouët F, Underwood P, Metson J, Imre R, Mechtler K, Katis VL, Nasmyth K.

Mol Cell, 2009

doi:10.1016/j.molcel.2009.02.028.