Spatial genomics maps the structure, nature and evolution of cancer clones.

Lomakin A, Svedlund J, Strell C, Gataric M, Shmatko A, Rukhovich G, Park JS, Ju YS, Dentro S, Kleshchevnikov V, Vaskivskyi V, Li T, Bayraktar OA, Pinder S, Richardson AL, Santagata S, Campbell PJ, Russnes H, Gerstung M, Nilsson M, Yates LR.

Nature, 2022

doi:10.1038/s41586-022-05425-2.

Identification of a pleiotropic effect of ADIPOQ on cardiac dysfunction and Alzheimer's disease based on genetic evidence and health care records.

Paik H, Lee J, Jeong CS, Park JS, Lee JH, Rappoport N, Kim Y, Sohn HY, Jo C, Kim J, Cho SB.

Transl Psychiatry, 2022

doi:10.1038/s41398-022-02144-0.

Cell2location maps fine-grained cell types in spatial transcriptomics.

Kleshchevnikov V, Shmatko A, Dann E, Aivazidis A, King HW, Li T, Elmentaite R, Lomakin A, Kedlian V, Gayoso A, Jain MS, Park JS, Ramona L, Tuck E, Arutyunyan A, Vento-Tormo R, Gerstung M, James L, Stegle O, Bayraktar OA.

Nat Biotechnol, 2022

doi:10.1038/s41587-021-01139-4.

PoSTcode: Probabilistic image-based spatial transcriptomics decoder

Gataric M, Park JS, Li T, Vaskivskyi V, Svedlund J, Strell C, Roberts K, Nilsson M, Yates LR, Bayraktar O, Gerstung M.

2021

doi:10.1101/2021.10.12.464086.

A map of transcriptional heterogeneity and regulatory variation in human microglia.

Young AMH, Kumasaka N, Calvert F, Hammond TR, Knights A, Panousis N, Park JS, Schwartzentruber J, Liu J, Kundu K, Segel M, Murphy NA, McMurran CE, Bulstrode H, Correia J, Budohoski KP, Joannides A, Guilfoyle MR, Trivedi R, Kirollos R, Morris R, Garnett MR, Timofeev I, Jalloh I, Holland K, Mannion R, Mair R, Watts C, Price SJ, Kirkpatrick PJ, Santarius T, Mountjoy E, Ghoussaini M, Soranzo N, Bayraktar OA, Stevens B, Hutchinson PJ, Franklin RJM, Gaffney DJ.

Nat Genet, 2021

doi:10.1038/s41588-021-00875-2.

Low-Level Brain Somatic Mutations Are Implicated in Schizophrenia.

Kim MH, Kim IB, Lee J, Cha DH, Park SM, Kim JH, Kim R, Park JS, An Y, Kim K, Kim S, Webster MJ, Kim S, Lee JH.

Biol Psychiatry, 2021

doi:10.1016/j.biopsych.2021.01.014.

SHP2 mutations induce precocious gliogenesis of Noonan syndrome-derived iPSCs during neural development in vitro.

Ju Y, Park JS, Kim D, Kim B, Lee JH, Nam Y, Yoo HW, Lee BH, Han YM.

Stem Cell Res Ther, 2020

doi:10.1186/s13287-020-01709-4.

SWATH-MS analysis of cerebrospinal fluid to generate a robust battery of biomarkers for Alzheimer's disease.

Park SA, Jung JM, Park JS, Lee JH, Park B, Kim HJ, Park JH, Chae WS, Jeong JH, Choi SH, Baek JH.

Sci Rep, 2020

doi:10.1038/s41598-020-64461-y.

Brain somatic mutations observed in Alzheimer's disease associated with aging and dysregulation of tau phosphorylation.

Park JS, Lee J, Jung ES, Kim MH, Kim IB, Son H, Kim S, Kim S, Park YM, Mook-Jung I, Yu SJ, Lee JH.

Nat Commun, 2019

doi:10.1038/s41467-019-11000-7.

Human glioblastoma arises from subventricular zone cells with low-level driver mutations.

Lee JH, Lee JE, Kahng JY, Kim SH, Park JS, Yoon SJ, Um JY, Kim WK, Lee JK, Park J, Kim EH, Lee JH, Lee JH, Chung WS, Ju YS, Park SH, Chang JH, Kang SG, Lee JH.

Nature, 2018

doi:10.1038/s41586-018-0389-3.