09 Jul 2025 - 09 Jul 2025
Protein complexes play a crucial role in driving biological functions and processes, making it important to gain insights into proteins and their higher-order assemblies.Complex Portal is a curated resource designed to offer insights into proteins and their higher-level complexes. In this webinar we will introduce the portal, address how we define protein complexes, demonstrate how to search complexes using accession numbers, or keywords specific search, perform organism-specific searches, explore examples of complex details pages including the Complex Viewer and link-outs to related databases. We will also look at the new ‘star-rating’ given to complexes, use the Complex Navigator to compare orthologous and paralogous complexes and introduce the predicted human complexes from huMAP3.0 and MuSIC maps.
Webinar
Virtual
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27 Oct 2025 - 31 Oct 2025
This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI-predicted macromolecular structure data.Structural biology, determining the three-dimensional shapes of biomacromolecules and their complexes, can tell us a lot about how these molecules function and the roles they play within a cell. Data derived from structure determination experiments and Artificial Intelligence (AI)-assisted structure prediction enables life-science researchers to address a wide variety of questions. This course explores bioinformatics data resources and tools for the investigation, analysis, and interpretation of both experimentally determined and predicted biomacromolecular structures. It will focus on how best to analyse and interpret available structural data to gain useful information given specific research contexts. The course content will also cover predicting function and exploring interactions with other macromolecules.Successful participants may be sent materials prior to the course. These might include pre-recorded talks and required reading or online training that will be essential to fully engage with the course.
Course
Virtual
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17 Nov 2025 - 21 Nov 2025
A guide to the technology, analysis workflows, tools, and resources for next generation sequencing data analysis.This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data. The main focus will be on introducing sequence informatics, re-sequencing, differences between short- and long-read sequencing, and variant calling during the analysis of higher-eukaryotes, with an emphasis on human genetic research. Throughout the week, more advanced topics will introduce genome graphs, pangenomics, the creation of pipelines, automation, and the scaling-up of analysis experiments.Practical sessions will be run on datasets prepared by the trainers, not on personal research data. Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses. They will also learn the basics to create their own pipelines and use pipelines openly available.
Course
EMBL-EBI
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