The latest Expression Atlas release is here and contains new RNA-seq datasets including a featured experiment from a collaboration with the DIAMONDS project as well as proteomics data from our cooperation with PRIDE. 

This release has 4424 datasets in total, spanning microarray gene expression profiling, RNA-seq (1406) and proteomics (93) datasets. Of these, 340 report baseline gene expression, across a total of 47 different organisms and 4084 datasets showing differential comparisons across 51 different organisms. The overall species count has increased to 66 as we have also added a new species in this release – Drosophila pseudoobscura (check the experiment here).

New datasets

This release adds 109 new datasets in total, which contain both baseline and differential experiments. One exciting example is a transcription profiling of rat liver and kidney, where changes in gene expression are examined following exposure to different chemicals. Another interesting dataset we’ve added examines the transcriptomic response of cocoa to water deficit. Our new addition baseline experiments include a wide range of datasets, for example the transcriptome profiling of various organs at different developmental stages in rice and RNA-Sequencing of whole blood samples from children with a range of acute febrile illnesses.

Collaboration

The latest baseline study belongs to our new featured collection European Diagnostic Transcriptomic Library (EDTL), which is part of a collaboration with the DIAMONDS project (Diagnosis and Management of Febrile Illness using RNA Personalised Molecular Signature Diagnosis). EDTL is being developed as a curated database of whole blood RNA expression data from human subjects with a wide range of infectious and inflammatory conditions. 

We have also added 11 new baseline proteomics datasets focusing on colorectal cancer in collaboration with the PRIDE team at EMBL-EBI – check out an example here!

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