{"id":728,"date":"2024-03-26T22:30:23","date_gmt":"2024-03-26T22:30:23","guid":{"rendered":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/?page_id=728"},"modified":"2025-10-22T06:22:50","modified_gmt":"2025-10-22T06:22:50","slug":"cryozoo","status":"publish","type":"page","link":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/projects\/cryozoo\/","title":{"rendered":"CRYOZOO"},"content":{"rendered":"\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p class=\"vf-lede\">Animal Cell Line Biobank for Conservation and Research<\/p>\n<!--\/vf-lede-->\n\n\n\n\n<p><\/p>\n\n\n\n<p class=\"vf-lede\"><strong><em>Collaborative project of Pompeu Fabra University (UPF), Barcelona ZOO Foundation, Barcelona Museum of Natural Science, and EMBL<\/em><\/strong>.<\/p>\n<!--\/vf-lede-->\n\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"vf-figure wp-block-image size-large is-style-default\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/PB-Image-CRYOZOO-1024x576.jpg\" alt=\"\" class=\"wp-image-1441\" style=\"object-fit:cover\" srcset=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/PB-Image-CRYOZOO-1024x576.jpg 1024w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/PB-Image-CRYOZOO-300x169.jpg 300w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/PB-Image-CRYOZOO-768x432.jpg 768w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/PB-Image-CRYOZOO.jpg 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p>The CRYOZOO project is an initiative dedicated to conservation and research to protect the biological diversity of our planet. Our objective is to create a stable biobank of animal cell lines, giving priority to endangered species worldwide. The genome (WGS), transcriptome (RNA-seq), and epigenome (ATAC-seq, and ChIP-seq) are being analysed. The induced pluripotent stem cell lines (iPSC) are created from a selected subset.<\/p>\n\n\n\n<p>The development and maintenance of a biobank is a key element in the fight for the maintenance of the biodiversity of species and ecosystems through research. The study derived from these cell lines, as well as the successful generation of iPSCs, has a direct impact on conservation through genetic studies of individuals, populations and ecosystems, as well as in biomedicine.<\/p>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<h3 class=\"wp-block-heading\">EMBL PI and contact person<\/h3>\n\n\n<div class=\"vf-content-hub-html\" data-cache=\"df70e411\">\n      <!-- Generated by: http:\/\/content.embl.org\/api\/v1\/pattern.html?filter-content-type=person&amp;filter-field-contains%5Bfield_person_full_name%5D=James%20Sharpe&amp;filter-fields-empty=field_person_visible_internally&amp;filter-ref-entity%5Bfield_person_positions%5D%5Btitle%5D=&amp;filter-ref-entity%5Bfield_person_positions%5D%5Bfield_position_primary%5D=1&amp;hide%5Bteam%2Corcid%5D=1&amp;limit=1&amp;pattern=vf-profile-inline -->\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"87698\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60027035.jpg?itok=GrjElgNp\" alt=\"image of James Sharpe\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/james-sharpe\" class=\"vf-profile__link\">James Sharpe<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Head of EMBL Barcelona\n        <\/p>\n      \n      \n      \n      \n      \n      \n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/87698\/87698\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n  <\/div>\n\n\n\n<p><\/p>\n\n\n\n<a href=\"https:\/\/cryozoo.org\/\" target=\"_blank\">\n<button class=\"vf-button vf-button--primary\">CRYOZOO.ORG<\/button>\n<\/a>\n<!--\/vf-button-->\n\n\n\n\n<p><\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-1\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<div class=\"vf-grid | vf-grid__col-3\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<figure class=\"vf-figure wp-block-image size-full\"><a href=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/Cryozoo_biobanked-species_2024.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"466\" height=\"373\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/Cryozoo_biobanked-species_2024.jpg\" alt=\"\" class=\"wp-image-1358\" srcset=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/Cryozoo_biobanked-species_2024.jpg 466w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/Cryozoo_biobanked-species_2024-300x240.jpg 300w\" sizes=\"auto, (max-width: 466px) 100vw, 466px\" \/><\/a><\/figure>\n\n<\/div>\n<\/div>\n\n\n<div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<figure class=\"vf-figure wp-block-image size-large\"><a href=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CRYOZOO-NUMBER-SLIDE-PB.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"292\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CRYOZOO-NUMBER-SLIDE-PB-1024x292.jpg\" alt=\"\" class=\"wp-image-1440\" srcset=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CRYOZOO-NUMBER-SLIDE-PB-1024x292.jpg 1024w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CRYOZOO-NUMBER-SLIDE-PB-300x86.jpg 300w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CRYOZOO-NUMBER-SLIDE-PB-768x219.jpg 768w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CRYOZOO-NUMBER-SLIDE-PB.jpg 1066w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"vf-figure wp-block-image size-large\"><a href=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_IPSC-generated-so-far.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"190\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_IPSC-generated-so-far-1024x190.jpg\" alt=\"\" class=\"wp-image-1360\" srcset=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_IPSC-generated-so-far-1024x190.jpg 1024w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_IPSC-generated-so-far-300x56.jpg 300w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_IPSC-generated-so-far-768x143.jpg 768w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_IPSC-generated-so-far.jpg 1431w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<p>Species of 7 generated iPSC lines<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p><strong>Main Objectives<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cryopreservation of viable cell lines from captive and wild species with priority to the most threatened vertebrates in the IUCN red list.<\/li>\n\n\n\n<li>Characterization of the karyotype and molecular phenotypes for these cell lines, such as genome, epigenome and transcriptomics for genomic and comparative studies .<\/li>\n\n\n\n<li>Study and Promote Research in cell reprogramming techniques for iPSCs generation.<\/li>\n\n\n\n<li>Contribute to final preservation of species through informed management, both from the ecological and the population view through studies and analysis of molecular data.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:27px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>CRYOZOO is linked to global initiatives<\/strong><\/p>\n\n\n\n<figure class=\"vf-figure wp-block-image size-large is-resized is-style-default\"><a href=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_global-initiatives.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"453\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_global-initiatives-1024x453.jpg\" alt=\"\" class=\"wp-image-1359\" style=\"width:600px\" srcset=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_global-initiatives-1024x453.jpg 1024w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_global-initiatives-300x133.jpg 300w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_global-initiatives-768x340.jpg 768w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/CryoZoo_global-initiatives.jpg 1397w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>How do we work? <\/strong>The research projects to generate new cell lines or use our existing ones are being presented to the <strong>Scientific and ethics committee<\/strong> composed of all the members of the CRYOZOO founding institutions. Approved projects need to sign the Material Transfer Agreement, which is specific for each cell line.<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Partners<\/h3>\n\n\n\n<p>Pompeu Fabra University (UPF)<\/p>\n\n\n\n<p>Barcelona ZOO Foundation<\/p>\n\n\n\n<p>Barcelona Museum of Natural Science<\/p>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-1\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":714,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-title-left-aligned.php","meta":{"_acf_changed":false,"footnotes":""},"embl_taxonomy":[],"class_list":["post-728","page","type-page","status-publish","hentry"],"acf":[],"embl_taxonomy_terms":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages\/728","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/comments?post=728"}],"version-history":[{"count":57,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages\/728\/revisions"}],"predecessor-version":[{"id":76501,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages\/728\/revisions\/76501"}],"up":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages\/714"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/media?parent=728"}],"wp:term":[{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/embl_taxonomy?post=728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}