{"id":1334,"date":"2024-05-07T09:30:34","date_gmt":"2024-05-07T09:30:34","guid":{"rendered":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/?page_id=1334"},"modified":"2024-05-15T14:37:50","modified_gmt":"2024-05-15T14:37:50","slug":"sizeevolve","status":"publish","type":"page","link":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/projects\/sizeevolve\/","title":{"rendered":"SizeEvolve"},"content":{"rendered":"\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p class=\"vf-lede\">Planarian body size: Why are some animals small and others large?<\/p>\n<!--\/vf-lede-->\n\n\n\n\n<p>  <\/p>\n\n\n\n<figure class=\"vf-figure wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"538\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/SizeEvolve_HanhVu_project-page-1024x538.jpg\" alt=\"\" class=\"wp-image-1981\" srcset=\"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/SizeEvolve_HanhVu_project-page-1024x538.jpg 1024w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/SizeEvolve_HanhVu_project-page-300x158.jpg 300w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/SizeEvolve_HanhVu_project-page-768x403.jpg 768w, https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-content\/uploads\/2024\/05\/SizeEvolve_HanhVu_project-page.jpg 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>Body size is a defining feature of every animal with important implications for physiology, ecology and evolution. Yet, how each species gets its characteristic size and why size varies so dramatically across the animal kingdom is not well understood. This project aims to address these questions by harnessing the extreme body size diversity of planarian flatworms. First, we will determine size-dependent GRNs in the model species <em>Schmidtea mediterranea<\/em> using single-cell RNA\/ATAC approaches developed in the lab last year. Second, we will investigate how size-dependent GRNs have evolved in different planarian species and whether these changes underlie planarian body size diversification.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Collaborators<\/h3>\n\n\n\n<p><a href=\"https:\/\/www.ebi.ac.uk\/about\/teams\/nonvertebrate-genomics\/\" data-type=\"link\" data-id=\"https:\/\/www.ebi.ac.uk\/about\/teams\/nonvertebrate-genomics\/\">Sarah Dyer, Non-vertebrate Genomics<\/a>, EMBL-EBI Hinxton<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<h3 class=\"wp-block-heading\">Project lead<\/h3>\n\n\n<div class=\"vf-content-hub-html\" data-cache=\"40b76a89\">\n      <!-- Generated by: http:\/\/content.embl.org\/api\/v1\/pattern.html?filter-content-type=person&amp;filter-field-contains%5Bfield_person_full_name%5D=hanh&amp;filter-fields-empty=field_person_visible_internally&amp;filter-ref-entity%5Bfield_person_positions%5D%5Btitle%5D=&amp;filter-ref-entity%5Bfield_person_positions%5D%5Bfield_position_primary%5D=1&amp;hide%5Bteam%2Cemail%2Corcid%5D=1&amp;limit=1&amp;pattern=vf-profile-inline -->\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"115316\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60036340.jpg?itok=dcSww6nn\" alt=\"image of Hanh Vu\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/hanh-vu\" class=\"vf-profile__link\">Hanh Vu<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Group Leader\n        <\/p>\n      \n      \n      \n      \n      \n      \n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/115316\/115316\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n  <\/div>\n\n\n\n<p><\/p>\n\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":714,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-title-left-aligned.php","meta":{"_acf_changed":false,"footnotes":""},"embl_taxonomy":[],"class_list":["post-1334","page","type-page","status-publish","hentry"],"acf":[],"embl_taxonomy_terms":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages\/1334","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/comments?post=1334"}],"version-history":[{"count":15,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages\/1334\/revisions"}],"predecessor-version":[{"id":2211,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages\/1334\/revisions\/2211"}],"up":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/pages\/714"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/media?parent=1334"}],"wp:term":[{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/planetary-biology\/wp-json\/wp\/v2\/embl_taxonomy?post=1334"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}