{"id":1318,"date":"2023-10-26T13:26:31","date_gmt":"2023-10-26T13:26:31","guid":{"rendered":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/?page_id=1318"},"modified":"2025-04-04T12:02:53","modified_gmt":"2025-04-04T12:02:53","slug":"members","status":"publish","type":"page","link":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/members\/","title":{"rendered":"Members"},"content":{"rendered":"\n
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At the core of the Alliance are our Members\u00a0 – faculty from EMBL and the Stanford University School of Medicine. <\/p>\n\n\n\n\n\n

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Their combined expertise spans a broad spectrum of life science research from structural biology and bioinformatics, to chemistry, imaging and genomics. They are committed to the exchange of information to solve complex biomedical challenges together.<\/p>\n\n\n\n

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View their research interests and collaborations below.<\/strong><\/h3>\n\n\n\n
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\n \n \n Contact us\n \n <\/path>\n <\/svg>\n <\/a>\n <\/h3>\n \n \n

\r\n\r\nWe are always open to accepting new members from EMBL and Stanford University. If our projects or interests match yours, contact us – we would love to hear from you.\r\n\r\n<\/p>\n <\/div>\n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n
\n\n \"Headshot\n

\n Monther Abu-Remaileh<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Projects:<\/strong><\/p>\n\n\n\n

Networks of subcellular compartments in health and disease<\/a> (with Sinem Saka).<\/p>\n\n\n\n

Mitochondrial thermal proteome profiling for the study of oncometabolites interactome<\/a> (with Mikhail Savitski and Sinem Saka)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"\"\n

\n Alexander Aulehla<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Connecting organizational scales from the bottom-up to investigate emergence in embryonic pattern formation<\/a>\u00a0(with James Ferrell & Anna Erzberger).<\/p>\n\n\n\n

Assessing the inter-kingdom conservation of lifespan variants evolved in yeast <\/a>(with Dmitri Petrov).<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"\"\n

\n Alex Bateman<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

ncRNA annotation<\/a> (with Mike Cherry)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Carolyn Bertozzi<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Dissecting NGLY1 deficiency<\/a> (with Lars Steinmetz) <\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Maria Bernabeu Aznar<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Identification and in vitro <\/em>functional characterization of human protective polymorphisms against severe malaria (with Elizabeth Egan)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Ami Bhatt<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong> <\/p>\n\n\n\n

Developing global interaction networks of microbiome-encoded genes (with Peer Bork)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Vivek Bhalla<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Using and developing innovative methodologies to discover novel molecular mechanisms and therapies for kidney health.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Matthieu Boulard<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Molecular basis of chromatin-based silencing and cellular readout of cytosine methylation.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Peer Bork<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project: <\/strong><\/p>\n\n\n\n

Developing global interaction networks of microbiome-encoded genes (with Ami Bhatt)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Howard Chang<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Dissecting molecular mechanisms of epigenetic silencing<\/a> (with Edith Heard)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n
\n\n \"Headshot\n

\n Mike Cherry<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

ncRNA annotation<\/a>  (with Alex Bateman) <\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Wah Chiu<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

The development of cryo-EM methodology to determine 3D cellular structures. We also work on the EMDataResource which is an open access database for 3D EM for developing software, data standards and validation methods.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Isidro Cortes Ciriano<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project: <\/strong><\/p>\n\n\n\n

Quantifying tumour evolution and fitness landscapes<\/a> (with Christina Curtis)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Markus Covert<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Integrative model of human cell signalling<\/a> (with Evangelia Petsalaki)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Christina Curtis<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Projects:<\/strong><\/p>\n\n\n\n

<\/a><\/a>Quantifying tumour evolution and fitness landscapes<\/a> (with Isidro Cort\u00e9s-Ciriano)<\/p>\n\n\n\n

Deciphering Mechanisms and Rates of Chromosomal Instability in Gastric Cancer<\/a> (with Jan Korbel)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"\"\n

\n Martha Cyert<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Discovering new calcium-dependent signaling pathways in humans that are regulated by the calcineurin protein phosphatase.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n Ron Davis<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project: <\/strong><\/p>\n\n\n\n

Personalizing dilated cardiomyopathy<\/a> (with Lars Steinmetz & Utkan Demirci)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Utkan Demirci<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Personalizing dilated cardiomyopathy<\/a> (with Lars Steinmetz & Ron Davis)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Claire Deo<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Developing novel molecular tools for advanced biological imaging by combining synthetic chemistry and protein engineering<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Gautam Dey<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project<\/strong>:<\/p>\n\n\n\n

Cell cycle adaptation to aneuploidy: How do cells adapt to carrying an extra chromosome?<\/a> (with Gavin Sherlock)<\/p>\n\n\n\n

Visualizing parasitic plasmid interactions with host nuclear components<\/a> (with Gavin Sherlock)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Jos\u00e9 Dinneny<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Understanding the response of roots to water-limiting conditions and across different organizational scales from the individual cell type to the whole plant.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Olivier Duss<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Assembly mechanisms and function of protein-RNA complexes at the single-molecule level<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Elizabeth Egan<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Identification and in vitro <\/em>functional characterization of human protective polymorphisms against severe malaria (with Maria Bernabeu)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Jan Ellenberg<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project<\/strong>:<\/p>\n\n\n\n

Advancing imaging technology (with Tobias Meyer)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Anna Erzberger<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Connecting organizational scales from the bottom-up to investigate emergence in embryonic pattern formation<\/a> (with Alexander Aulehla & James Ferrell)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"headshot\n

\n Dean Felsher<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

How oncogenes initiate and sustain tumorigenesis including: how oncogene activation causes tumor regression, and how tumors escape dependence on oncogenes.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n James Ferrell<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Connecting organizational scales from the bottom-up to investigate emergence in embryonic pattern formation (<\/a>with Alexander Aulehla & Anna Erzberger)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Judith Frydman<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/strong><\/p>\n\n\n\n

Co-translational nascent chain modifications and their adaptation to cellular stress<\/a> (with Misha Savitski & Lars Steinmetz)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Margaret Fuller<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages: including regulation of cell type specific transcription programs, cell-cell communication, and the role of differential mRNA processing and translational control in progression from one cell state to the next.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n Eileen Furlong<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Genome regulation and topology during embryonic development including: chromatin topology, chromatin remodelling during cell fate decisions, variation and plasticity in regulatory networks, developmental enhancers, and single cell genomics.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n
\n\n \"Andrew\n

\n Andrew Gentles<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Computational approaches to understand biological systems using genomic and proteomic data across populations. Most of our work is in cancer and neurodegenerative disease, but we love to hear about any interesting questions!<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Miriam Goodman<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/strong><\/p>\n\n\n\n

Keith HodgsonDeciphering the molecular events responsible for touch, pain, and position sensation in C. elegans<\/em>.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"\"\n

\n James Hackett<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Understanding the mechanistic interplay between genome regulation, chromatin and environmental cues (microbiome), with emphasis on intergenerational effects<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n Matthias Hentze<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Using biochemical and systems-level approaches to investigate the connections between gene expression and cell metabolism, and their roles in human disease.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Edith Heard<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Dissecting molecular mechanisms of epigenetic silencing<\/a> (with Howard Chang)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
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\n\n \"Headshot\n

\n Keith Hodgson<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/strong><\/p>\n\n\n\n

Integrated structural biology <\/a>(with Matthias Wilmanns)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n
\n\n \"Headshot\n

\n Susan Holmes<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Modern statistics for modern biology<\/a> (with Wolfgang Huber)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n KC Huang<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Disentangling gene function & organisation in the microbiome<\/a> (with Nassos Typas)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Wolfgang Huber<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Modern statistics for modern biology<\/a> (with Susann Holmes)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Ruth Huettenhain<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

How G protein-coupled receptors decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n Maya Kasowski<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Using scMulti-omics to probe clinical outcome of child leukemia treatment<\/a> (with Judith Zaugg)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Teri Klein<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Comprehensive pharmacogenetic analysis using real world data<\/a> (with Ellen McDonagh)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Arnaud Krebs<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Transcription Factor cooperativity atlas<\/a> (with Anshul Kundaje).<\/p>\n\n\n\n

Learning the cis-regulatory code at single-molecule resolution (with Anshul Kundaje)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Jan Korbel<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Somatic mosaicisms in cancer <\/a>(with Alex Urban)<\/p>\n\n\n\n

Deciphering Mechanisms and Rates of Chromosomal Instability in Gastric Cancer<\/a> (with Christina Curtis)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Brian Kobilka<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Characterizing the structure and mechanism of G-Protein Coupled Receptors (GPCRs).<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n \"Headshot\n

\n Anshul Kundaje<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Projects:<\/strong><\/p>\n\n\n\n

Integrative machine learning to decipher genome function<\/a> (with Oliver Stegle)<\/p>\n\n\n\n

Transcription Factor cooperativity atlas<\/a> (with Arnaud Krebs)<\/p>\n\n\n\n

Learning the cis-regulatory code at single-molecule resolution (with Arnaud Krebs)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n
\n\n \"Headshot\n

\n Jin Billy Li<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

T<\/a>RNA editing. We are interested in ADAR-mediated RNA editing, for both its biological function in dsRNA-mediated innate immunity and its utility as a tool for transcriptome engineering. (with Anshul Kundaje)<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n
\n\n \"Headshot\n

\n Julia Mahamid<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

We employ state-of-the-art cellular cryo-electron tomography to study phase-separated assemblies in cell biology and to advance our understanding of the molecular organization of the cytoplasm.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\n
\n\n \"Headshot\n

\n Jos\u00e9 M\u00e1rquez<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

We develop methods and software for high-throughput, automated crystallography and use them to study the structure of sensing and signalling molecules.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Ellen McDonagh<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Comprehensive pharmacogenetic analysis using real world data<\/a> (with Teri Klein).<\/p>\n\n\n\n

Systematic extraction of standard-of-care treatment from real world data to evaluate novel therapeutic targets (with Russ Altman).<\/p>\n\n<\/div>\n<\/div>\n\n\n

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\n\n \"Headshot\n

\n Tobias Meyer<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Advancing imaging technology (with Jan Ellenberg)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Stephen Montgomery<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

M<\/a>apping the effects of genetic variants from genes to cells to disease<\/a> (with Oliver Stegle)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Victoria Parikh<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project<\/strong>:<\/p>\n\n\n\n

Personalizing dilated cardiomyopathy<\/a> (with Lars Steinmetz)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Evangelia Petsalaki<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Integrative model of human cell signalling <\/a>(with Markus Covert)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Robert Prevedel<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Advanced optical techniques for deep tissue microscopy. In particular, we work in the fields of multi-photon microscopy, active wave-front shaping, photo-acoustics as well as computational imaging. Looking for collaboration in cell & developmental biology and neuroscience, where our novel imaging approaches can give new insights.<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Marlene Rabinovitch<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Multiomics for pulmonary hypertension (with Judith Zaugg)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Georgia Rapti<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Dissecting the cellular and molecular mechanisms of nervous system assembly and the underlying glia\u2013neuron crosstalk, using advanced genetics, genomics and live imaging approaches.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Kacper Rogala<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project<\/strong>:<\/p>\n\n\n\n

Watching protein\/protein- protein\/ligand-interaction dynamics within the mTOR signaling pathway resolved in time and space<\/a> (with Gergely Papp)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Santiago Rompani<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Studying the function of visual circuits using functional imaging, genetics, virology and behavioural assays<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Mikhail Savitski<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Mitochondrial thermal proteome profiling for the study of oncometabolites interactome<\/a> (with Monther Abu-Remaileh)<\/p>\n\n\n\n

Co-translational nascent chain modifications and their adaptation to cellular stress<\/a> (with Judith Frydman & Lars Steinmetz).<\/p>\n\n\n\n

Proteomics analysis of the stress response in vertebrate organs during aging (with Dan Jarosz & Anne Brunet).<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Sinem Saka<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Networks of subcellular compartments in health and disease<\/a> (with Monther Abu-Remaileh)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Gavin Sherlock<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Cell cycle adaptation to aneuploidy: How do cells adapt to carrying an extra chromosome?<\/a> (with Gautam Dey).<\/p>\n\n\n\n

Visualizing parasitic plasmid interactions with host nuclear components<\/a> (with Gautam Dey)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Skiniotis Skiniotis<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Developing a mechanistic understanding of signal translation at the cell membrane using structural biology, biochemistry and simulation methods<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Mike Snyder<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Genetic regulation of chromatin (with Judith Zaugg)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Oliver Stegle<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Projects:<\/strong><\/p>\n\n\n\n

Integrative machine learning to decipher genome function<\/a> (with Anshul Kundaje)<\/p>\n\n\n\n

Mapping the effects of genetic variants from genes to cells to disease<\/a> (with Stephen Montgomery)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Lars Steinmetz <\/h3>\n \n \n

EMBL & Stanford<\/p>\r\n

<\/p>\r\n

EMBL<\/a>
\r\nStanford<\/a><\/p><\/div>\n \n \n\n \n<\/article>\n\n\n\n

Project:s<\/strong><\/p>\n\n\n\n

Personalizing dilated cardiomyopathy<\/a> (with Ron Davis, Utkan Demirci, Euan Ashley, Victoria Parikh)<\/p>\n\n\n\n

Dissecting NGLY1 deficiency<\/a> (with Carolyn Bertozzi)<\/p>\n\n\n\n

Co-translational nascent chain modifications and their adaptation to cellular stress<\/a> (with Misha Savitski & Judith Frydman)<\/p>\n\n\n\n

Unlocking the potential of image cell sorting for functional genomics and cell biology<\/a> (with Anna Kreshuk)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Aaron Straight<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Genome specialization in dinoflagellates<\/a><\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Katrin Svensson<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Physiological regulation of metabolism in single cells<\/a> (with Theo Alexandrov)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Nassos Typas<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project<\/strong>:<\/p>\n\n\n\n

Disentangling gene function & organisation in the microbiome<\/a> (with KC Huang)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Alex Urban<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project<\/strong>:<\/p>\n\n\n\n

Somatic mosaicisms <\/a>(with Jan Korbel)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Kevin Wang<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interests:<\/strong><\/p>\n\n\n\n

Gene expression and epigenetics: how DNA methylation, chromatin modifications, and RNA influence chromatin dynamics to affect gene regulation.<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Matthias Wilmanns<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Integrated structural biology<\/a> (with Keith Hodgson)<\/p>\n\n\n\n

Efficient in-cellulo X-ray data acquisition using advanced sample enrichment and delivery tool (with Tina Cohen & Mark Hunter).<\/p>\n\n\n\n

Long-range reaction intermediates channeling in multi-enzyme complexes and allosteric regulation (with Soichi Wakatsuki).<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
\n
\n\n
\n\n \"Headshot\n

\n Yunzhi Peter Yang<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interest:<\/strong><\/p>\n\n\n\n

Developing bio-inspired biomaterials and platform technologies to engineer tissues and organs<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Judith Zaugg<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Projects<\/strong>:<\/p>\n\n\n\n

Using scMulti-omics to probe clinical outcome of child leukemia treatment<\/a> (with Maya Kasowski)<\/p>\n\n\n\n

Multiomics for pulmonary hypertension (with Marlene Rabinovitch)

Genetic regulation of chromatin (with Mike Snyder)<\/p>\n\n\n\n

Dissecting gene regulatory networks driving cell type differentiation in a marine annelid (with Detlev Arendt and Bo Wang).<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Jan Skotheim<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project<\/strong>:<\/p>\n\n\n\n

Using image-assisted cell sorting to determine the molecular mechanism controlling nuclear size<\/a> (with Diana Ordonez and Lars Steinmetz)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Diana Ordonez<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Using image-assisted cell sorting to determine the molecular mechanism controlling nuclear size<\/a> (with Jan Skotheim and Lars Steinmetz)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Gergely Papp<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Watching protein\/protein- protein\/ligand-interaction dynamics within the mTOR signaling pathway resolved in time and space<\/a> (with Kacper Rogala)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Anna Kreshuk<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Deep Learning-Powered Study of 3D Tissue Structures and Molecular Cues in Breast Cancer Initiation<\/a> (with Garry Nolan)<\/p>\n\n\n\n

Unlocking the potential of image cell sorting for functional genomics and cell biology <\/a>(with Lars Steinmetz\/Stanford)<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Garry Nolan<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Deep Learning-Powered Study of 3D Tissue Structures and Molecular Cues in Breast Cancer Initiation<\/a> (with Anna Kreshuk)<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Andrew McCarthy<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Mechanism of CO2<\/sub> fixation reaction by enoyl-CoA carboxylases\/reductase <\/a>(with Soichi Wakatsuki).<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Soichi Wakatsuki<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Mechanism of CO2<\/sub> fixation reaction by enoyl-CoA carboxylases\/reductase <\/a>(with Andrew McCarthy).<\/p>\n\n\n\n

Long-range reaction intermediates channeling in multi-enzyme complexes and allosteric regulation (with Matthias Wilmanns).<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Detlev Arendt<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Dissecting gene regulatory networks driving cell type differentiation in a marine annelid (with Judith Zaugg and Bo Wang).<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Anna L Gloyn<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interest:<\/strong><\/p>\n\n\n\n

We are an inter-disciplinary team of basic and clinical scientists with shared interests in using molecular genetics as a tool to uncover novel biology. We use a variety of different approaches to address important challenges in the field, which range from studies that work genome wide to those which are focused on specific genes and even precise nucleotide changes to understand their impact on pancreatic islet biology.<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Peter Sarnow<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interest:<\/strong><\/p>\n\n\n\n

Roles for microRNAs and circular RNAs during RNA virus infections.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Xiaoke Chen<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interest:<\/strong><\/p>\n\n\n\n

The Chen lab studies circuitry and molecular mechanisms underlying motivated behaviors, and how maladaptive changes in these circuits leads to neuropsychiatric disorders.<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Lucy Erin O\u2019Brien<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interest:<\/strong><\/p>\n\n\n\n

The O’Brien lab studies spatial and temporal dynamics of stem cell lineages in vivo using cutting-edge live imaging approaches.<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Christopher Barnes<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interest:<\/strong><\/p>\n\n\n\n

Research in our lab is aimed at defining the structural correlates of broad and potent antibody-mediated neutralization of viruses. We combine biophysical and structural methods (e.g., cryo-EM), protein engineering, and in vivo approaches to understand how enveloped viruses infect host cells and elicit antigen-specific immune responses. <\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Vikas Trivedi<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interest:<\/strong><\/p>\n\n\n\n

The Trivedi group aims to understand the self-organisation of cells, fundamental to metazoan development, through comparative study of embryos and organoids that generate a global coordinate system de novo<\/em>.<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Bo Wang<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Dissecting gene regulatory networks driving cell type differentiation in a marine annelid (with Judith Zaugg and Detlev Arendt).<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"Headshot\n

\n Tino Pleiner<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Research Interest:<\/strong><\/p>\n\n\n\n

The Pleiner lab combines molecular, cellular and structural biology to study the pathways and molecular machines that regulate protein homeostasis, with a particular focus on membrane protein biogenesis and quality control at the human endoplasmic reticulum. We develop alpaca-derived nanobodies as intracellular tools to study and reverse failure of protein misfolding and aggregation associated with neurodegeneration and ageing.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"\"\n

\n Dmitri Petrov<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Assessing the inter-kingdom conservation of lifespan variants evolved in yeast<\/a> (with Alexander Aulehla).<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Russ Altman<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Systematic extraction of standard-of-care treatment from real world data to evaluate novel therapeutic targets (with Ellie McDonagh).<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Daniel Jarosz<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong>
Proteomics analysis of the stress response in vertebrate organs during aging (with Mischa Savitski & Anne Brunet).<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

\n
\n\n
\n\n \"\"\n

\n Anne Brunet<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Proteomics analysis of the stress response in vertebrate organs during aging (with Mischa Savitski & Dan Jarosz)..<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Ellen Yeh<\/a>\n <\/h3>\n \n

\n Stanford <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Comparative cell evolution in nitrogen-fixing endosymbioses (with Yannick Schwab and Gautam Dey).<\/p>\n\n\n\n

<\/p>\n\n<\/div>\n<\/div>\n\n\n

\n
\n\n
\n\n \"\"\n

\n Yannick Schwab<\/a>\n <\/h3>\n \n

\n EMBL <\/p>\n \n \n \n\n \n<\/article>\n\n\n\n

Project:<\/strong><\/p>\n\n\n\n

Comparative cell evolution in nitrogen-fixing endosymbioses (with Ellen Yeh and Gautam Dey).<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":7,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-title-left-aligned.php","meta":{"_acf_changed":false,"footnotes":""},"embl_taxonomy":[],"class_list":["post-1318","page","type-page","status-publish","hentry"],"acf":[],"embl_taxonomy_terms":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/pages\/1318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/comments?post=1318"}],"version-history":[{"count":312,"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/pages\/1318\/revisions"}],"predecessor-version":[{"id":8275,"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/pages\/1318\/revisions\/8275"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/media?parent=1318"}],"wp:term":[{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/life-science-alliance\/wp-json\/wp\/v2\/embl_taxonomy?post=1318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}