{"id":66,"date":"2020-11-02T18:37:53","date_gmt":"2020-11-02T18:37:53","guid":{"rendered":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/?page_id=66"},"modified":"2026-01-28T08:29:43","modified_gmt":"2026-01-28T08:29:43","slug":"user-stories","status":"publish","type":"page","link":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/user-stories\/","title":{"rendered":"User Stories &#038; Publications"},"content":{"rendered":"\n<div class=\"vf-grid | vf-grid__col-1\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p><strong>We are proud to have supported so many great user projects and incredible science over the past years!<\/strong><\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p>In September 2021 we welcomed our first onsite user Pia Lavriha who came to use our correlative microscopy services: <em>\u201cThe Imaging Centre specialists provided the training and insight into how things are supposed to look. I could then develop a feeling for, and expertise in, applying these techniques independently. This is the most important aspect for me.\u201d<\/em> <a href=\"https:\/\/www.embl.org\/news\/lab-matters\/embl-imaging-centre-welcomes-first-external-user\/?_ga=2.10986100.1568324639.1638362213-142691117.1607530318\" data-type=\"URL\" data-id=\"https:\/\/www.embl.org\/news\/lab-matters\/embl-imaging-centre-welcomes-first-external-user\/?_ga=2.10986100.1568324639.1638362213-142691117.1607530318\" class=\"docs-creator\">Read more<\/a>.<\/p>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"294\" height=\"300\" src=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2021\/12\/IC_220921-01-edited-scaled-e1638366723352-294x300.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" srcset=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2021\/12\/IC_220921-01-edited-scaled-e1638366723352-294x300.jpg 294w, https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2021\/12\/IC_220921-01-edited-scaled-e1638366723352.jpg 560w\" sizes=\"auto, (max-width: 294px) 100vw, 294px\" \/>\n    <h3 class=\"vf-profile__title\" >\n                    Pia Lavriha            <\/h3>\n    \n                <p class=\"vf-profile__text\" >\n                ETH Zurich and Paul Scherrer Institute, Switzerland            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"300\" height=\"275\" src=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2022\/01\/DSC_0864_edit-scaled-e1641553103503-300x275.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" srcset=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2022\/01\/DSC_0864_edit-scaled-e1641553103503-300x275.jpg 300w, https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2022\/01\/DSC_0864_edit-scaled-e1641553103503-1024x940.jpg 1024w, https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2022\/01\/DSC_0864_edit-scaled-e1641553103503-768x705.jpg 768w, https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2022\/01\/DSC_0864_edit-scaled-e1641553103503.jpg 1400w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>\n    <h3 class=\"vf-profile__title\" >\n                    Danny Ionescu            <\/h3>\n    \n                <p class=\"vf-profile__text\" >\n                Leibniz\u00a0Institute of Freshwater Ecology and Inland Fisheries, Germany            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p>Our first onsite pilot user for light microscopy services was visiting in October 2021 &#8211; Danny Ionescu: <em>&#8220;For me, it was a fantastic experience, both from a technological and scientific aspect but also due to the engagement of the Imaging Centre team who made all efforts to address my research needs and provide methods specifically tailored for my unique samples.&#8221;<\/em><\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p><em>\u201cAlthough we did not succeed in capturing the structure of the ribosome primed for bypassing of MGS13 mRNA, we did determine the structure of the bacterial ribosome at an unprecedented resolution of 1.55 \u00c5 thanks to the incredible facilities available at the EMBL Imaging Centre and the fantastic work carried out by Simon Fromm.\u201d&nbsp;<\/em><a href=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/user-stories\/kate-oconnor\/\" target=\"_blank\" rel=\"noreferrer noopener\">Read more<\/a>.<\/p>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2024\/02\/1603439148338-300x300.jpeg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" srcset=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2024\/02\/1603439148338-300x300.jpeg 300w, https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2024\/02\/1603439148338-150x150.jpeg 150w, https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2024\/02\/1603439148338.jpeg 560w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>\n    <h3 class=\"vf-profile__title\" >\n                    Kate O\u2019Connor            <\/h3>\n    \n                <p class=\"vf-profile__text\" >\n                University College Cork, Ireland\u00a0            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"200\" height=\"200\" src=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2024\/02\/roberto-marotta-6ab28336.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" srcset=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2024\/02\/roberto-marotta-6ab28336.jpg 200w, https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2024\/02\/roberto-marotta-6ab28336-150x150.jpg 150w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/>\n    <h3 class=\"vf-profile__title\" >\n                    Roberto Marotta            <\/h3>\n    \n                <p class=\"vf-profile__text\" >\n                Electron Microscopy Facility of IIT, Italy            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p><em>\u201cAll&nbsp;the experiments, both grid screening and high-end data collections, have been performed virtually due to&nbsp;the COVID-19&nbsp;pandemic. Nevertheless, Dr. Simone Mattei was really helpful in evaluating our results. We could&nbsp;participate&nbsp;in remote&nbsp;and assist&nbsp;Dr. Simon Fromm&nbsp;in the various stages of sample screening and data collection. This experience&nbsp;was very helpful and instructive.\u201d&nbsp;<\/em><a href=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/user-stories\/roberto-marotta\/\" target=\"_blank\" rel=\"noreferrer noopener\">Read more<\/a>.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p><em>\u201cThanks to the use of MINFLUX, we could obtain data on the localization of the full-length CSPP1, as well as its fragments. Before the development of the MINFLUX technology, it was not possible to determine whether the protein localises on the inside or outside of microtubules, least of all individual protein domains.\u201d&nbsp;<\/em><a href=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/user-stories\/cyntha-van-den-berg\/\" target=\"_blank\" rel=\"noreferrer noopener\">Read more<\/a>.<\/p>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"100\" height=\"140\" src=\"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-content\/uploads\/2024\/02\/Cyntha_van_den_Berg.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" >\n                    Cyntha van den Berg            <\/h3>\n    \n                <p class=\"vf-profile__text\" >\n                University of Utrecht, the Netherlands            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"vf-divider\">\n\n\n\n<div class=\"vf-grid | vf-grid__col-2\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<h2 class=\"wp-block-heading\">Publications &amp; Preprints<\/h2>\n\n\n\n<p>Papers listed include publications and preprints of users of the Imaging Centre and of the interim service operation by EMBL&#8217;s cryo-EM platform, as well as publications on our work on workflow and technology development.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">2026<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Puig-Tint\u00f3 M, Ortiz S, Meek S, Coray R, Betancur LI, Hern\u00e1ndez AC, Castellet A, Kramer E, Hoess P, Mund M, Molina-Ribagorda A, Izquierdo-Serra M, Oliva B, de Marco A, Ries J, Casta\u00f1o-D\u00edez D, Manzo C, Gallego O. <strong>Continuum architecture dynamics of vesicle tethering in exocytosis.<\/strong> Cell 2026 Jan 16:S0092-8674(25)01374-1. <a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(25)01374-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867425013741%3Fshowall%3Dtrue\" data-type=\"link\" data-id=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(25)01374-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867425013741%3Fshowall%3Dtrue\">doi: 10.1016\/j.cell.2025.11.038<\/a>.<\/li>\n\n\n\n<li>Alcaide-Jim\u00e9nez A, Canals A, Baudin F, Machon C, Fabrega-Ferrer M, Bantysh O, Perez-Luque R, Murciano B, Mohammad AA, Rowse MJ, Farracciolo JM, Krukonis ES, Mueller CW, Coll M. <strong>Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes.<\/strong> Sci Adv 2026 Jan 16;12(3):eadx9680. <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adx9680\" target=\"_blank\" rel=\"noreferrer noopener\">DOI:10.1126\/sciadv.adx9680<\/a>.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">2025<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u010cavka I, Woglar A, Wu YL, Durmus EB, Sloat L, Gros A, L\u00f3pez CP, Hecht F, Villeneuve AM, Ries J, K\u00f6hler S. <strong>Multi-step implementation of meiotic crossover patterning.<\/strong>\u00a0bioRxiv November 13, 2025.\u00a0<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.11.12.687980v1\" data-type=\"link\" data-id=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.11.12.687980v1\">doi: 10.1101\/2025.11.12.687980<\/a>.<\/li>\n\n\n\n<li>Geetha SS, \u010cavka I, Dello Stritto MR, Graf A, Macha T, Krakolinig H, K\u00f6hler S, Jantsch V. <strong>Bloom helicase contributes to successful crossover formation with both catalytic and structural roles in Caenorhabditis elegans meiosis.<\/strong> <a href=\"https:\/\/europepmc.org\/search?query=JOURNAL%3A%22Nucleic%20Acids%20Res%22\">Nucleic Acids Res<\/a>, 53(19):gkaf1030,\u00a001 Oct 2025. <a href=\"https:\/\/doi.org\/10.1093\/nar\/gkaf1030\" data-type=\"link\" data-id=\"https:\/\/doi.org\/10.1093\/nar\/gkaf1030\">doi: 10.1093\/nar\/gkaf1030.<\/a><\/li>\n\n\n\n<li>Zhang W, Latham AP, Ronchi P, Schnorrenberg S, H\u00e9rich\u00e9 J, Huang Z, Hossain MJ, Morero NR, Pflaumer H, Hantsche-Grininger M, Schwab Y, Sali A, Ellenberg J. <strong>Hydrophobic interactions of FG-nucleoporins are required for dilating nuclear membrane pores into selective transport channels after mitosis.\u00a0<\/strong>bioRxiv\u00a0September 08, 2025. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.09.08.674396v1\" data-type=\"link\" data-id=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.09.08.674396v1\">doi:10.1101\/2025.09.08.674396<\/a>.<\/li>\n\n\n\n<li>Sharma A, Sau A, Dave S, Roychowdhury S,\u00a0Schnorrenberg S, Chowdhury R, Hutten S, Dormann D, Musser SM. <strong>Clustering within a single-component biomolecular condensate.\u00a0<\/strong>bioRxiv August 22, 2025.\u00a0<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.08.18.670948v1\">doi:10.1101\/2025.08.18.670948<\/a>.<\/li>\n\n\n\n<li>Dehingia B, Milewska-Pucha\u0142a M, Janowski M, Rafiee, MR, Abbas M, Piotrowska A, Senge J, Blaut P,&nbsp;Walsh D, Severino J, Chaudhury D, Iqbal S, Montiel-Manriquez R, Jankowska S, Zare P, Huber W, Xu J, Casellas R,&nbsp;<strong>Zimmermann T<\/strong>, D\u0142otko P, \u2026 P\u0119kowska A. (2025).&nbsp;<strong>RNA-binding proteins mediate the maturation of chromatin topology during differentiation.<\/strong>&nbsp;Nature cell biology&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/s41556-025-01735-5#Ack1\" data-type=\"link\" data-id=\"https:\/\/www.nature.com\/articles\/s41556-025-01735-5#Ack1\">doi: 10.1038\/s41556-025-01735-5<\/a>.<\/li>\n\n\n\n<li>Macias M, Condeminas M, Torner C, Pluta R, Ruiz L, Aragon E, de R\u00e9gil MR, Martin-Malpartida P, Pous J, Pardon E, Steyaert J,&nbsp;Fromm S. (2025) <strong>SMAD4 nanobodies as tools for investigating SMAD structures and modulating SMAD function.<\/strong>&nbsp;Research Square&nbsp;<a href=\"https:\/\/www.researchsquare.com\/article\/rs-6354474\/v1\" data-type=\"link\" data-id=\"https:\/\/www.researchsquare.com\/article\/rs-6354474\/v1\">doi:10.21203\/rs.3.rs-6354474\/v1.<\/a><\/li>\n\n\n\n<li>Patra G, Harastani M, Samejima K, Remnant L, Troffer-Charlier N, Crucifix C, Durand A, Marechal N, Lutz Y, Steyer AM, Yang Z, Hagen WJH, Earnshaw WC, Eltsov M. (2025) <strong>Organisation of axial regions of isolated mitotic chromosomes visualised by cryo correlative light and electron tomography.<\/strong>&nbsp;<em>bioRxiv<\/em>, <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.02.06.636497v1.full.pdf\" data-type=\"link\" data-id=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.02.06.636497v1.full.pdf\">doi:10.1101\/2025.02.06.636497<\/a>.<\/li>\n\n\n\n<li>Hammer M, Skrzypczyk L, Wohlfart S, Ackermann BC, Geisweid L, Pohl SW, Karaivanova M, Herth J, Augustin VA, Studier-Fischer A, Sackmann T, Kaulen L, Steyer A, Mier W, Steel DH, Xue K, Auffarth GU, Uhl P. (2025) <strong>Methotrexate-Loaded Liposomal Formulation Enables 6-Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model.<\/strong> Adv Healthc Mater. 2025 Sep 25:e03230. <a href=\"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.202503230\" data-type=\"link\" data-id=\"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.202503230\">doi: 10.1002\/adhm.202503230<\/a>.<\/li>\n\n\n\n<li>Vidmar V, Borde C, Bruno L, Miropolskaya N, Takacs M, Batisse C, Saint-Andr\u00e9 C, Zhu C, Esp\u00e9li O, Lamour V, Weixlbaumer A. (2025) <strong>DNA topoisomerase I acts as supercoiling sensor for bacterial transcription elongation.<\/strong> Nat Struct Mol Biol. 2025 Dec 1. <a href=\"https:\/\/www.nature.com\/articles\/s41594-025-01703-5#Ack1\" data-type=\"link\" data-id=\"https:\/\/www.nature.com\/articles\/s41594-025-01703-5#Ack1\">doi: 10.1038\/s41594-025-01703-5<\/a>.<\/li>\n\n\n\n<li>Herbsleb L, Wild D, Gr\u00f6ger H, Schubert T, Steyer AM, Hennies J, Alves F, Feldmann C, Walter A. (2025) <strong>3D correlative light and electron microscopy reveals the uptake and processing of inorganic-organic hybrid nanoparticles into cancer cells.<\/strong> Nanomedicine. 2025 Oct 22;70:102872. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1549963425000735?via%3Dihub\" data-type=\"link\" data-id=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1549963425000735?via%3Dihub\">doi: 10.1016\/j.nano.2025.102872.<\/a><\/li>\n\n\n\n<li>Wachsmuth-Melm M, Peterl S, O&#8217;Riain A, Makroczyov\u00e1 J, Fischer K, Krischuns T, Vale-Costa S, Amorim MJ, Chlanda P. (2025) <strong>Visualizing influenza A virus assembly by in situ cryo-electron tomography.<\/strong> Nat Commun. 2025 Oct 23;16(1):9394. doi: <a href=\"https:\/\/www.nature.com\/articles\/s41467-025-65117-z#Abs1\" data-type=\"link\" data-id=\"https:\/\/www.nature.com\/articles\/s41467-025-65117-z#Abs1\">10.1038\/s41467-025-65117-z.<\/a><\/li>\n\n\n\n<li>Deng A, Cunnison R, Carrique L, G\u00fcnl F, Paddon E, Staeyart J, Nguyen Duc D, Grimes JM, Robb N, Keown JR. (2025) <strong>Structural and functional characterisation of the Crimean-Congo Haemorrhagic Fever Virus RNA Dependent RNA Polymerase.&nbsp;<\/strong>bioRxiv&nbsp;<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.10.21.683639v1\" data-type=\"link\" data-id=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.10.21.683639v1\">doi:&nbsp;10.1101\/2025.10.21.683639<\/a><\/li>\n\n\n\n<li>Sokke Rudraiah P, Herbsleb L, Salakova M, Gr\u00f6ger H, Steyer AM, Alves F, Feldmann C, Walter A. (2025) <strong>Combining Correlative Cryogenic Fluorescence and Electron Microscopy and Correlative Cryogenic Super-Resolution Fluorescence and X-Ray Tomography-Novel Complementary 3D Cryo-Microscopy Across Scales to Reveal Nanoparticle Internalization Into Cancer Cells. <\/strong>Microsc Res Tech. 2025 Sep 1. <a href=\"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/jemt.70071\">doi: 10.1002\/jemt.70071.<\/a><\/li>\n\n\n\n<li>Fitzpatrick LW, Woythe L, Huang Z, Schnorrenberg S, Zimmermann T, Albertazzi L. (2025) <strong>MINFLUX: \u03bcs and nm precision 3D tracking of dynamic lipid mobility on nanoparticles.<\/strong> Nanoscale. 2025 Jul 3. <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2025\/nr\/d5nr00948k\" data-type=\"link\" data-id=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2025\/nr\/d5nr00948k\">doi: 10.1039\/d5nr00948k<\/a><\/li>\n\n\n\n<li>Eshriew E, Kumpula E, Sah-Teli SK, Abettan A, Djurabekova A, Sharma V, Huiskonen JT. (2025) <strong>In situ Structure of the Human Gap Junction.&nbsp;<\/strong>bioRxiv&nbsp;<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.07.04.663179v1\" data-type=\"link\" data-id=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.07.04.663179v1\">doi:&nbsp;10.1101\/2025.07.04.663179<\/a>.&nbsp;<\/li>\n\n\n\n<li>Ullrich A, Schneider J, Braz JM, Neu E, Staffen N, Stanek M, Bl\u00e1hov\u00e1 J, Hove T, Albert T, Allikalt A, L\u00f6ber S, Bhardwaj K, Rodriguez-Rosado S, Fink E, Rasmussen T, H\u00fcbner H, Inoue A, Shoichet BK, Basbaum AI, B\u00f6ttcher B, Weikert D, Gmeiner P. (2025) <strong>Discovery of a functionally selective serotonin receptor (5-HT<sub>1A<\/sub>R) agonist for the treatment of pain.<\/strong> Sci Adv. 2025 Jun 20;11(25):eadv9267. <a href=\"https:\/\/doi.org\/10.1126\/sciadv.adv9267\">doi: 10.1126\/sciadv.adv9267<\/a><\/li>\n\n\n\n<li>Sau A, Schnorrenberg S, Huang Z, Bandyopadhyay D, Sharma A, G\u00fcrth CM, Dave S, Musser SM. (2025) <strong>Overlapping nuclear import and export paths unveiled by two-colour MINFLUX. <\/strong>Nature. 2025 Apr;640(8059):821-827. <a href=\"https:\/\/doi.org\/10.1038\/s41586-025-08738-0\">doi: 10.1038\/s41586-025-08738-0.<\/a><\/li>\n\n\n\n<li>Soni K, Horvath A, Dybkov O, Schwan M, Trakansuebkul S, Flemming D, Wild K, Urlaub H, Fischer T, Sinning I. (2025) <strong>Structures of aberrant spliceosome intermediates on their way to disassembly.<\/strong> Nat Struct Mol Biol. 2025 Jan 20. <a href=\"https:\/\/doi.org\/10.1038\/s41594-024-01480-7\">doi: 10.1038\/s41594-024-01480-7<\/a>.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">2024<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Chakraborty P, Ib\u00e1\u00f1ez de Opakua A, Purslow JA<strong>, <\/strong>Fromm SA, Chatterjee D, Zachrdla M, Zhuang S, Puri S, Wolozin B, Zweckstetter M. (2024) <strong>GSK3\u03b2 phosphorylation catalyzes the aggregation of tau into Alzheimer&#8217;s disease-like filaments.<\/strong> Proc Natl Acad Sci U S A. 2024 Dec 24;121(52):e2414176121. <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2414176121\" data-type=\"link\" data-id=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2414176121\">doi: 10.1073\/pnas.2414176121<\/a>.<\/li>\n\n\n\n<li>Vallbracht M, Bodmer BS, Fischer K, Makroczyova J, Winter SL, Wendt L, Wachsmuth-Melm M, Hoenen T, Chlanda P. (2024) <strong>Nucleocapsid assembly drives Ebola viral factory maturation and dispersion.<\/strong> Cell. 2025 Feb 6;188(3):704-720.e17. <a href=\"https:\/\/doi.org\/10.1016\/j.cell.2024.11.024\">doi: 10.1016\/j.cell.2024.<\/a><\/li>\n\n\n\n<li>Karimi-Farsijani S, Sharma K, Ugrina M, Kuhn L, Pfeiffer PB, Haupt C, Wiese S, Hegenbart U, Sch\u00f6nland SO, Schwierz N, Schmidt M, F\u00e4ndrich M. (2024) <strong>Cryo-EM structure of a lysozyme-derived amyloid fibril from hereditary amyloidosis. <\/strong>Nat Commun. 2024 Nov 7;15(1):9648. <a href=\"https:\/\/doi.org\/10.1038\/s41467-024-54091-7\">doi: 10.1038\/s41467-024-54091-7.<\/a><\/li>\n\n\n\n<li>Roth P, Jeckelmann JM, Fender I, Ucurum Z, Lemmin T, Fotiadis D. (2024) <strong>Structure and mechanism of a phosphotransferase system glucose transporter.<\/strong> Nat Commun. 2024 Sep 12;15(1):7992. <a href=\"https:\/\/doi.org\/10.1038\/s41467-024-52100-3\">doi: 10.1038\/s41467-024-52100-3.<\/a><\/li>\n\n\n\n<li>Morris K, Bulovaite E, Kaizuka T, Schnorrenberg S, Adams CT, Komiyama N, Mendive-Tapia L, Grant SGN, Horrocks MH. 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(2024) <strong>Ice thickness control and measurement in the VitroJet for time-efficient single particle structure determination.<\/strong> J Struct Biol. 2024 Dec;216(4):108139. <a href=\"https:\/\/doi.org\/10.1016\/j.jsb.2024.108139\">doi: 10.1016\/j.jsb.2024.108139.<\/a><\/li>\n\n\n\n<li>Gemin O, Gluc M, Rosa H, Purdy M, Niemann M, Peskova Y, Mattei S, Jomaa A. (2024) <strong>Ribosomes hibernate on mitochondria during cellular stress.<\/strong> Nat Commun. 2024 Oct 8;15(1):8666. <a href=\"https:\/\/doi.org\/10.1038\/s41467-024-52911-4\">doi: 10.1038\/s41467-024-52911-4.&nbsp;<\/a><\/li>\n\n\n\n<li>Karimi-Farsijani S, Pfeiffer PB, Banerjee S, Baur J, Kuhn L, Kupfer N, Hegenbart U, Sch\u00f6nland SO, Wiese S, Haupt C, Schmidt M, F\u00e4ndrich M. (2024) <strong>Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis. <\/strong>Nat Commun. 2024 Jun 15;15(1):5121. <a href=\"https:\/\/doi.org\/10.1038\/s41467-024-49520-6\">doi: 10.1038\/s41467-024-49520-6<\/a>.<\/li>\n\n\n\n<li>Zimmermann T. (2024) <strong>Setting up a light microscopy core facility: Facility design.<\/strong> J Microsc. 2024 Jun;294(3):255-267. <a href=\"https:\/\/doi.org\/10.1111\/jmi.13301\">doi: 10.1111\/jmi.13301<\/a>.&nbsp;<\/li>\n\n\n\n<li>Power RM, Tschanz A, Zimmermann T, Ries J. (2024) <strong>Build and operation of a custom 3D, multicolor, single-molecule localization microscope.<\/strong> Nat Protoc. 2024 Aug;19(8):2467-2525. <a href=\"https:\/\/doi.org\/10.1038\/s41596-024-00989-x\">doi: 10.1038\/s41596-024-00989-x.<\/a><\/li>\n\n\n\n<li>Khare S, Villalba MI, Canul-Tec JC, Cajiao AB, Kumar A, Backovic M, Rey FA, Pardon E, Steyaert J, Perez C, Reyes N. 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(2024) <strong>Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.<\/strong> Nat Commun. 2024 Jan 12;15(1):486. <a href=\"https:\/\/doi.org\/10.1038\/s41467-023-44489-0\">doi: 10.1038\/s41467-023-44489-0<\/a>.<\/li>\n\n\n\n<li>Andreotti G, Baur J, Ugrina M, Pfeiffer PB, Hartmann M, Wiese S, Miyahara H, Higuchi K, Schwierz N, Schmidt M, F\u00e4ndrich M. (2024) <strong>Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils.<\/strong> J Mol Biol. 2024 Feb 15;436(4):168441. <a href=\"https:\/\/doi.org\/10.1016\/j.jmb.2024.168441\" data-type=\"link\" data-id=\"https:\/\/doi.org\/10.1016\/j.jmb.2024.168441\">doi: 10.1016\/j.jmb.2024.168441.<\/a><\/li>\n\n\n\n<li>Gritti N, Power RM, Graves A<em>, <\/em>Huisken J<em>.<\/em> (2024) <strong>Image restoration of degraded time-lapse microscopy data mediated by near-infrared imaging.<\/strong>&nbsp;<em>Nat Methods<\/em>. doi: <a href=\"https:\/\/doi.org\/10.1038\/s41592-023-02127-z\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1038\/s41592-023-02127-z<\/a><\/li>\n\n\n\n<li>Gemin O,&nbsp;Armijo V,&nbsp;Hons M,&nbsp;Bissardon C,&nbsp;Linares R,&nbsp;&nbsp;Bowler MW, Wolff G,&nbsp;Kovalev K,&nbsp;Babenko A,&nbsp;Salo VT,&nbsp;Schneider S,&nbsp;Rossi C, Lecomte L,&nbsp;Deckers T, Lauzier K,&nbsp;Janocha R,&nbsp;Felisaz F,&nbsp;Sinoir J,&nbsp;Galej W,&nbsp;Mahamid J,&nbsp;M\u00fcller CW,&nbsp;Eustermann S,&nbsp;Mattei S,&nbsp;Cipriani F,&nbsp;Papp G. (2024) <strong>EasyGrid: A versatile platform for automated cryo-EM sample preparation and quality control. <\/strong>bioRxiv&nbsp;2024.01.18.576170;&nbsp;<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.01.18.576170v1\" target=\"_blank\" rel=\"noreferrer noopener\">doi:&nbsp;https:\/\/doi.org\/10.1101\/2024.01.18.576170<\/a><\/li>\n\n\n\n<li>Pfeiffer PB, Ugrina M, Schwierz N, Sigurdson CJ, Schmidt M, F\u00e4ndrich M. (2024) <strong>Cryo-EM Analysis of the Effect of Seeding with Brain-derived A\u03b2 Amyloid Fibrils.<\/strong> J Mol Biol. 2024 Feb 15;436(4):168422. <a href=\"https:\/\/doi.org\/10.1016\/j.jmb.2023.168422\" data-type=\"link\" data-id=\"https:\/\/doi.org\/10.1016\/j.jmb.2023.168422\">doi: 10.1016\/j.jmb.2023.168422<\/a>.<\/li>\n<\/ul>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\n2023<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<ul class=\"wp-block-list\">\n<li>Pfeiffer PB, Ugrina M, Schwierz N, Sigurdson CJ, Schmidt M, F\u00e4ndrich M. (2023) <strong>Cryo-EM Analysis of the Effect of Seeding with Brain-derived A\u03b2 Amyloid Fibrils<\/strong>. J Mol Biol, 436(4):168422, 28 Dec 2023. <a href=\"https:\/\/doi.org\/10.1016\/j.jmb.2023.168422\">doi: 10.1016\/j.jmb.2023.168422<\/a>. <\/li>\n\n\n\n<li>Torres-S\u00e1nchez L, G\u00e9ry Sana T, Decossas M, Hashem Y, Krasteva PV. (2023) <strong>Structures of the&nbsp;<em>P. aeruginosa<\/em>&nbsp;FleQ-FleN master regulators reveal large-scale conformational switching in motility and biofilm control.<\/strong> Proc Natl Acad Sci U S A, 120(50):e2312276120, 05 Dec 2023. <a href=\"https:\/\/www.pnas.org\/doi\/full\/10.1073\/pnas.2312276120\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1073\/pnas.2312276120<\/a>.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Power RM, Tschanz A, Zimmermann T, Ries J. (2023) <strong>Automated 3D multi-color single-molecule localization microscopy.<\/strong> bioRxiv, 24 Oct 2023. <a href=\"https:\/\/doi.org\/10.1101\/2023.10.23.563122\">doi: 10.1101\/2023.10.23.563122<\/a>.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Adamoski D, Dias MM, Ques\u00f1ay JEN, Yang Z, Zagoriy I, Steyer AM, Rodrigues CT, da Silva Bastos AC, da Silva BN, Costa RKE, de Abreu FMO, Islam Z, Cassago A, van Heel MG, Consonni SR, Mattei S, Mahamid J, Portugal RV, Ambrosio ALB, Dias SMG. (2023) <strong>Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection.<\/strong> Nat Struct Mol Biol, 30(12):1902-1912, 19 Oct 2023. <a href=\"https:\/\/www.nature.com\/articles\/s41594-023-01118-0#Ack1\" data-type=\"link\" data-id=\"https:\/\/www.nature.com\/articles\/s41594-023-01118-0#Ack1\">doi: 10.1038\/s41594-023-01118-0<\/a>. <\/li>\n\n\n\n<li>Prevost MS, Barilone N, Dejean de la B\u00e2tie G, Pons S, Ayme G, England P, Gielen M, Bontems F, Pehau-Arnaudet G, Maskos U, Lafaye P, Corringer PJ. (2023) <strong>An original potentiating mechanism revealed by the cryo-EM structures of the human \u03b17 nicotinic receptor in complex with nanobodies.<\/strong> Nat Commun. 2023 Sep 25;14(1):5964. <a href=\"https:\/\/www.nature.com\/articles\/s41467-023-41734-4#Ack1\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1038\/s41467-023-41734-4.<\/a><\/li>\n\n\n\n<li>Juyoux P, Galdadas I, Gobbo D, von Velsen J, Pelosse M, Tully M, Vadas O, Gervasio FL, Pellegrini E, Bowler MW. (2023) <strong>Architecture of the MKK6-p38\u03b1 complex defines the basis of MAPK specificity and activation.<\/strong> Science. 2023 Sep 15;381(6663):1217-1225. <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.add7859\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1126\/science.add7859<\/a>.<\/li>\n\n\n\n<li>Mocaer K, Mizzon G, Gunkel M, Halavatyi A, Steyer A, Oorschot V, Schorb M, Le Kieffre C, Yee DP, Chevalier F, Gallet B, Decelle J, Schwab Y, Ronchi P. (2023) <strong>Targeted volume correlative light and electron microscopy of an environmental marine microorganism.<\/strong> Cell Sci. 2023 Aug 1;136(15):jcs261355. <a href=\"https:\/\/doi.org\/10.1242\/jcs.261355\">doi: 10.1242\/jcs.261355<\/a>.<\/li>\n\n\n\n<li>Fadeeva M, Klaiman D, Caspy I, Nelson N. (2023) <strong>Structure of Chlorella ohadii Photosystem II Reveals Protective Mechanisms against Environmental Stress.<\/strong> Cells 2023, 12(15), 1971. 31 July 2023. <a href=\"https:\/\/doi.org\/10.3390\/cells12151971\">DOI: 10.3390\/cells12151971<\/a>.<\/li>\n\n\n\n<li>Sharma K, Banerjee S, Savran D, Rajes C, Wiese S, Girdhar A, Schwierz N, Lee C, Shorter J, Schmidt M, Guo L, F\u00e4ndrich M. (2023) <strong>Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril.<\/strong> J Mol Biol, 435(18):168211, 20 Jul 2023. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283623003108?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1016\/j.jmb.2023.168211.<\/a><\/li>\n\n\n\n<li>Heerde T, Sch\u00fctz D, Lin YJ, M\u00fcnch J, Schmidt M, F\u00e4ndrich M. (2023) <strong>Cryo-EM structure and polymorphic maturation of a viral transduction enhancing amyloid fibril.<\/strong> Nat Commun. 2023 Jul 18;14(1):4293. <a href=\"https:\/\/www.nature.com\/articles\/s41467-023-40042-1#Ack1\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1038\/s41467-023-40042-1.&nbsp;<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Hennies J, Lleti JMS, Pape C, Bekbayev S, Gross V, Kreshuk A, Schwab Y. (2023) <strong>CebraEM: A practical workflow to segment cellular organelles in volume SEM datasets using a transferable CNN-based membrane prediction<\/strong>. bioRxiv, 06 Apr 2023. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2023.04.06.535829v1\">doi: 10.1101\/2023.04.06.535829v1<\/a>. <\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>van den Berg CM, Volkov VA, Schnorrenberg S, Huang Z, Stecker KE, Grigoriev I, Gilani S, Frikstad KM, Patzke S, Zimmermann T, Dogterom M, Akhmanova A. (2023) <strong>CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side.<\/strong> J Cell Biol. 2023 Apr 3;222(4):e202208062. <a href=\"https:\/\/rupress.org\/jcb\/article\/222\/4\/e202208062\/213861\/CSPP1-stabilizes-growing-microtubule-ends-and\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1083\/jcb.202208062<\/a>.<\/li>\n\n\n\n<li>Heerde T, Bansal A, Schmidt M, F\u00e4ndrich M. (2023) <strong>Cryo-EM structure of a catalytic amyloid fibril<\/strong>. Sci Rep, 13(1):4070, 11 Mar 2023. <a href=\"https:\/\/doi.org\/10.1038\/s41598-023-30711-y\">DOI: 10.1038\/s41598-023-30711-y<\/a>.<\/li>\n\n\n\n<li>Deguchi T, Iwanski MK, Schentarra EM, Heidebrecht C, Schmidt L, Heck J, Weihs T, Schnorrenberg S, Hoess P, Liu S, Chevyreva V, Noh KM, Kapitein LC, Ries J. (2023) <strong>TDirect observation of motor protein stepping in living cells using MINFLUX.<\/strong> Science, 379(6636):1010-1015, 09 Mar 2023. <a href=\"https:\/\/doi.org\/10.1126\/science.ade2676\">doi: 10.1126\/science.ade2676<\/a><\/li>\n\n\n\n<li>Fromm SA, O&#8217;Connor KM, Purdy M, Bhatt PR, Loughran G, Atkins JF, Jomaa A, Mattei S. (2023) <strong>The translating bacterial ribosome at 1.55\u2009\u00c5 resolution generated by cryo-EM imaging services.<\/strong> Nat Commun. 2023 Feb 25;14(1):1095. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36841832\/\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1038\/s41467-023-36742-3.<\/a><\/li>\n\n\n\n<li>Caspy I, Fadeeva M, Mazor Y, Nelson N. (2023) <strong>Structure of Dunaliella photosystem II reveals conformational flexibility of stacked and unstacked supercomplexes.<\/strong> Elife. 2023 Feb 17;12:e81150. <a href=\"https:\/\/doi.org\/10.7554\/eLife.81150\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.7554\/elife.81150<\/a>.<\/li>\n\n\n\n<li>Ganeva I, Lim K, Boulanger J, Hoffmann PC, Muriel O, Borgeaud AC, Hagen WJH, Savage DB, Kukulski W. (2023) <strong>The architecture of Cidec-mediated interfaces between lipid droplets. <\/strong>Cell Rep. 2023 Feb 15;42(2):112107. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211124723001183?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1016\/j.celrep.2023.112107<\/a>.&nbsp;<\/li>\n\n\n\n<li>Kalbermatter D, Jeckelmann JM, Wyss M, Shrestha N, Pliatsika D, Riedl R, Lemmin T, Plattet P, Fotiadis D. (2023) <strong>Structure and supramolecular organization of the canine distemper virus attachment glycoprotein. <\/strong>Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2208866120. <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2208866120?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.1073\/pnas.2208866120.<\/a><\/li>\n\n\n\n<li>Prouteau M, Bourgoint C, Felix J, Bonadei L, Sadian Y, Gabus C, Savvides SN, Gutsche I, Desfosses A, Loewith R. 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EMBO J. <a href=\"https:\/\/doi.org\/10.15252\/embj.2021108341\">doi: 10.15252\/embj.2021108341<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Lynn Radamaker,&nbsp;Sara Karimi-Farsijani,&nbsp;Giada Andreotti,&nbsp;Julian Baur,&nbsp;Matthias Neumann,&nbsp;Sarah Schreiner,&nbsp;Natalie Berghaus,&nbsp;Raoul Motika,&nbsp;Christian Haupt,&nbsp;Paul Walther,&nbsp;Volker Schmidt,&nbsp;Stefanie Huhn,&nbsp;Ute Hegenbart,&nbsp;Stefan O. Sch\u00f6nland,&nbsp;Sebastian Wiese,&nbsp;Clarissa Read,&nbsp;Matthias Schmidt&nbsp;&amp;&nbsp;Marcus F\u00e4ndrich (2021). <strong>Role of mutations and post-translational modifications in systemic AL amyloidosis studied by cryo-EM<\/strong>. Nat Communications. <a href=\"https:\/\/doi.org\/10.1038\/s41467-021-26553-9\">doi: 10.1038\/s41467-021-26553-9<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Ido Caspy, Ehud Neumann, Maria Fadeeva, Varda Liveanu, Anton Savitsky, Anna Frank, Yael Levi Kalisman, Yoel Shkolnisky, Omer Murik, Haim Treves, Volker Hartmann, Marc M. Nowaczyk, Wolfgang Schuhmann, Matthias R\u00f6gner, Itamar Willner, Aaron Kaplan, Gadi Schuster, Nathan Nelson, Wolfgang Lubitz, Rachel Nechushtai (2021) <strong><strong>Cryo-EM photosystem I structure reveals adaptation mechanisms to extreme high light in&nbsp;<em>Chlorella ohadii<\/em><\/strong><\/strong>. Nat Plants. <a href=\"https:\/\/doi.org\/10.1038\/s41477-021-00983-1\">doi: 10.1038\/s41477-021-00983-1<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Charlotte Guyomar, Gaetano D\u2019Urso, Sophie Chat, Emmanuel Giudice, Reynald Gillet (2021) <strong><strong>Structures of tmRNA and SmpB as they transit through the ribosome<\/strong><\/strong>. <em><em>Nat Commun&nbsp;12<strong>,&nbsp;<\/strong>4909. <\/em><\/em><a href=\"https:\/\/doi.org\/10.1038\/s41467-021-24881-4\"><\/a><a href=\"https:\/\/doi.org\/10.1038\/s41467-021-24881-4\">doi: 10.1038\/s41467-021-24881-4<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Stephan Hirschi, David Kalbermatter, Z\u00f6hre Ucurum, Thomas Lemmin, Dimitrios Fotiadis (2021) <strong><strong>Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin<\/strong><\/strong>. <em><em><em>Nat Commun<\/em>&nbsp;12<strong>,&nbsp;<\/strong>4107. <\/em><\/em><a href=\"https:\/\/doi.org\/10.1038\/s41467-021-24429-6\">https:\/\/doi.org\/10.1038\/s41467-021-24429-6<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Julien Bous, H\u00e9l\u00e8ne Orcel, Nicolas Floquet, C\u00e9dric Leyrat, Jos\u00e9phine Lai-Kee-Him, G\u00e9rald Gaibelet, Aur\u00e9lie Ancelin, Julie Saint-Paul, Stefano Trapani, Maxime Louet, R\u00e9my Sounier, H\u00e9l\u00e8ne D\u00e9m\u00e9n\u00e9, S\u00e9bastien Granier, Patrick Bron, Bernard Mouillac (2021) <strong><strong>Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex<\/strong><\/strong>. <em><em>Sci Adv. 7(21):eabg5628. <a href=\"https:\/\/doi.org\/10.1126\/sciadv.abg5628\">doi: 10.1126\/sciadv.abg5628<\/a><\/em><\/em><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Martin Obr, Clifton L Ricana, Nadia Nikulin, Jon-Philip R Feathers, Marco Klanschnig, Andreas Thader, Marc C Johnson, Volker M Vogt, Florian K M Schur, Robert A Dick (2021). <strong><strong>Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer<\/strong><\/strong>. <em><em>Nat Commun&nbsp;12 (1)<strong>,&nbsp;<\/strong>3226. <\/em>doi:<\/em>&nbsp;<a href=\"https:\/\/doi.org\/10.1038\/s41467-021-23506-0\" target=\"_blank\" rel=\"noreferrer noopener\">10.1038\/s41467-021-23506-0<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Joshua Hutchings, Viktoriya G. Stancheva, Nick R. Brown, Alan C. M. Cheung, Elizabeth A. 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(2021) <strong><strong>MDA5 autoimmune disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA<\/strong>. <\/strong><em><em>bioRxiv<\/em><\/em>. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.02.01.429133v1\"><\/a><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.02.01.429133v1\">doi.org\/10.1101\/2021.02.01.429133<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Kraushar ML, Krupp F, Harnett D, Turko P, Ambrozkiewicz MC, Sprink T, Imami K, G\u00fcnnigmann M, Zinnall U, Vieira-Vieira CH, Schaub T, M\u00fcnster-Wandowski A, B\u00fcrger J, Borisova E, Yamamoto H, Rasin MR, Ohler U, Beule D, Mielke T, Tarabykin V, Landthaler M, Kramer G, Vida I, Selbach M, Spahn CMT<strong>.<\/strong> (2021) <strong><strong>Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit<\/strong><\/strong>. <em>Mol Cell. 2021 Jan 21;81(2):304-322.e16<\/em>. <a href=\"https:\/\/doi.org\/10.1016\/j.molcel.2020.11.037\">doi.org\/10.1016\/j.molcel.2020.11.037<\/a><\/li>\n<\/ul>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\n2020<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<ul class=\"wp-block-list\">\n<li>McDowell MA, Heimes M, Fiorentino F, Mehmood S, Farkas \u00c1, Coy-Vergara J, Wu D, Bolla JR, Schmid V, Heinze R, Wild K, Flemming D, Pfeffer S, Schwappach B, Robinson CV, Sinning I. 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(2020) <strong>Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism<\/strong><em>. <\/em><em>eLife<\/em>. <a href=\"https:\/\/doi.org\/10.7554\/eLife.56185\">doi.org\/10.7554\/eLife.56185<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Moser von Filseck J, Barberi L, Talledge&nbsp; N, Johnson IE, Frost A,&nbsp; Lenz M,&nbsp; Roux A. (2020) <strong>Anisotropic ESCRT-III architecture governs helical membrane tube formation<\/strong><em>. <\/em><em>Nat Commun<\/em> 11, 1516.&nbsp;<a href=\"http:\/\/doi.org\/10.1038\/s41467-020-15327-4\">doi.org\/10.1038\/s41467-020-15327-4<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Bertin A, de Franceschi N, de la Mora E, Maiti S, Alqabandi M, Miguet N, di Cicco&nbsp; A, Roos W, Mangenot S, Weissenhorn W, Bassereau P. (2020)<strong> Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation<\/strong><em>. <\/em><em>Nat Commun<\/em> 11, 2663.&nbsp;<a href=\"http:\/\/doi.org\/10.1038\/s41467-020-16368-5\">doi.org\/10.1038\/s41467-020-16368-5<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Flaugnatti N, Rapisarda C , Rey M, Beauvois SG, Nguyen VA, Canaan S, Durand E, Chamot\u2010Rooke J, Cascales E, Fronzes R, Journet L. (2020) <strong>Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike<\/strong><em>. <\/em><em>The EMBO Journal<\/em> 39: 39: e104129,&nbsp;<a href=\"http:\/\/doi.org\/10.15252\/embj.2019104129\">doi.org\/10.15252\/embj.2019104129<\/a><\/li>\n\n\n\n<li>Cannac F, Qi C, Falschlunger J,&nbsp; Hausmann G, Basler K, Korkhov VM.&nbsp;(2020) <strong>Cryo-EM structure of the Hedgehog release protein Dispatched<\/strong>. <em>Science Advances<\/em>, Vol 6:16,&nbsp;<a href=\"http:\/\/doi.org\/10.1126\/sciadv.aay7928\">doi.org\/10.1126\/sciadv.aay7928<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Von K\u00fcgelgen A, Tang H, Hardy GG, Kureisaite-Ciziene D, Brun YV, Stansfeld PJ, Robinson CV, Bharat TAM (2020) <strong>In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer<\/strong><em>. <\/em><em>Cell<\/em>. 180 (2): 348-358, doi:&nbsp;<a href=\"https:\/\/doi.org\/10.1016\/j.cell.2019.12.006\">https:\/\/doi.org\/10.1016\/j.cell.2019.12.006<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Webster MW, Takacs M, Zhu C, Vidmar V, Eduljee A, Abdelkareem M, Weixlbaumer A. (2020) <strong>Structural basis of transcription-translation coupling and collision in bacteria<\/strong>. Science, Vol. 369, Issue 6509, pp. 1355-1359. doi: <a href=\"https:\/\/science.sciencemag.org\/content\/369\/6509\/1355\">10.1126\/science.abb5036<\/a><\/li>\n<\/ul>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\n2019<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<ul class=\"wp-block-list\">\n<li>Kollmer M, Close W, Funk L, Rasmussen J, Bsoul A, Schierhorn A, Schmidt M, Sigurdson CJ, Jucker M, F\u00e4ndrich M. (2019) <strong>Cryo-EM structure and polymorphism of A\u03b2amyloid fibrils purified from Alzheimer\u2019s brain tissue<\/strong>. <em>Nat Commun<\/em>. 10(1):4760. doi: <a href=\"https:\/\/www.nature.com\/articles\/s41467-019-12683-8\">10.1038\/s41467-019-12683-8<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Schmidt M, Wiese S, Adak V, Engler J, Agarwal S, Fritz G, Westermark P, Zacharias M, F\u00e4ndrich M. (2019)<strong> Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis<\/strong><em>. <\/em><em>Nat Commun<\/em>. 10(1): 5008. doi: <a href=\"https:\/\/www.nature.com\/articles\/s41467-019-13038-z\">10.1038\/s41467-019-13038-z<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Abdelkareem M, Saint-Andr\u00e9 C, Takacs M, Papai G, Crucifix C, Guo X, Ortiz J, Weixlbaumer A. (2019) <strong>Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation<\/strong>. <em>Mol Cell.<\/em> S1097-2765(19)30321-1 doi: <a href=\"https:\/\/doi.org\/10.1016\/j.molcel.2019.04.029\">10.1016\/j.molcel.2019.04.029<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Qi C, Sorrentino S, Medalia O, Korkhov VM. (2019) <strong>The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein<\/strong>. <em>Science<\/em>&nbsp;364(6438): 389-394 doi:&nbsp;<a href=\"https:\/\/doi.org\/10.1126\/science.aav0778\">10.1126\/science.aav0778<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Radamaker L, Lin YH, Annamalai K, Huhn S, Hegenbart U, Sch\u00f6nland SO, Fritz G, Schmidt M, F\u00e4ndrich M. (2019) <strong>Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis.<\/strong> <em>Nat Commun.<\/em> 10 (1):1103 doi: <a href=\"http:\/\/doi.org\/10.1038\/s41467-019-09032-0\">10.1038\/s41467-019-09032-0<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Liberta F, Loerch S, Rennegarbe M, Schierhorn A, Westermark P, Westermark GT, Hazenberg BPC, Grigorieff N, F\u00e4ndrich M, Schmidt M. (2019) <strong>Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids<\/strong>. <em>Nat Commun.<\/em> 10 (1):1104. doi:<a href=\"https:\/\/doi.org\/10.1038\/s41467-019-09033-z\">10.1038\/s41467-019-09033-z<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cuervo A, F\u00e0brega-Ferrer M, Mach\u00f3n C, Conesa JJ, Fern\u00e1ndez FJ, P\u00e9rez-Luque R, P\u00e9rez-Ruiz M, Pous J, Vega CM, Carrascosa JL, Coll M. (2019) <strong>Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism<\/strong>. <em>Nat Commun<\/em>. 10: 3746. doi: <a href=\"https:\/\/www.nature.com\/articles\/s41467-019-11705-9\">10.1038\/s41467-019-11705-9<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Qi C, Di Minin G, Vercellino I, Wutz A, Korkhov VM (2019) <strong>Structural basis of sterol recognition by human hedgehog receptor PTCH1<\/strong>. <em>Sci Adv.<\/em> 2019 Sep; 5(9): eaaw6490. doi: <a href=\"https:\/\/advances.sciencemag.org\/content\/5\/9\/eaaw6490\">10.1126\/sciadv.aaw6490<\/a><\/li>\n\n\n\n<li>Desfosses A, Venugopal H, Joshi T, Felix J, Jessop M, Jeong H, Hyun J, Heymann JB, Hurst MRH, Gutsche I, Mitra AK (2019) <strong>Atomic structures of an entire contractile injection system in both the extended and contracted states<\/strong>. <em>Nature Microbiology.<\/em> doi <a href=\"https:\/\/www.nature.com\/articles\/s41564-019-0530-6\">10.1038\/s41564-019-0530-6<\/a><\/li>\n\n\n\n<li>Krupp F, Said N, Huang YH, Loll B, B\u00fcrger J, Mielke T, Spahn CMT, Wahl MC. (2019) <strong>Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor<\/strong>. <em>Molecular Cell,<\/em> 74:1, 143-157. doi: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S109727651930036X?via%3Dihub\">10.1016\/j.molcel.2019.01.016<\/a><\/li>\n<\/ul>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\n2018<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<ul class=\"wp-block-list\">\n<li>Oosterheert W, van Bezouwen LS, Rodenburg RNP, Granneman J, F\u00f6rster F, Mattevi A, Gros P. (2018) <strong>Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction.<\/strong> <em>Nat Commun.<\/em> 9(1):4337. doi: <a href=\"https:\/\/www.nature.com\/articles\/s41467-018-06817-7\">10.1038\/s41467-018-06817-7<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Hutchings J, Stancheva V, Miller EA, Zanetti G. (2018) <strong>Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape.<\/strong> <em>Nat Commun<\/em>. 9(1):4154. doi: <a href=\"https:\/\/www.nature.com\/articles\/s41467-018-06577-4\">10.1038\/s41467-018-06577-4<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Abascal-Palacios G, Ramsay EP, Beuron F, Morris E, Vannini A. (2018) <strong>Structural basis of RNA polymerase III transcription initiation.<\/strong> <em>Nature<\/em> 553(7688):301-306. doi: <a href=\"https:\/\/www.nature.com\/articles\/nature25441\">10.1038\/nature25441<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Elad, N, Baron S, Peleg Y, Albeck S, Grunwald J, Raviv G, Shakked Z, Zimhony O, Diskin R (2018) <strong>Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3\u2009\u00c5 resolution<\/strong>. <em>Molecular Cell<\/em>, 74:1. doi: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S109727651930036X?via%3Dihub\">10.1016\/j.molcel.2019.01.016<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>B\u00f6ttcher B, Nassal M. (2018) <strong>Structure of Mutant Hepatitis B Core Protein Capsids with Premature Secretion Phenotype<\/strong>. <em>JMB<\/em>, 430:24. doi: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283618308684?via%3Dihub\">10.1016\/j.jmb.2018.10.018<\/a><\/li>\n<\/ul>\n\n<\/div>\n<\/details>\n\n\n\n<hr class=\"vf-divider\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-title-left-aligned.php","meta":{"_acf_changed":false,"footnotes":""},"embl_taxonomy":[],"class_list":["post-66","page","type-page","status-publish","hentry"],"acf":[],"embl_taxonomy_terms":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/pages\/66","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/comments?post=66"}],"version-history":[{"count":173,"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/pages\/66\/revisions"}],"predecessor-version":[{"id":72221,"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/pages\/66\/revisions\/72221"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/media?parent=66"}],"wp:term":[{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/imaging-centre\/wp-json\/wp\/v2\/embl_taxonomy?post=66"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}