EMBL Imaging Centre

Open access to cutting-edge electron and light microscopy

We provide researchers from Europe and beyond with a synergistic portfolio of imaging services including cryo-EM, super-resolution and intravital microscopy to enable new ground-breaking research that crosses the scales of biology.

Cryo-Electron Microscopy

FEI Titan Krios G3 (Credit: EMBL Photolab/Marietta Schupp)

EMBL Heidelberg hosts a cryo-electron microscopy (cryo-EM) service platform, available for use by external scientists with both single particle and tomography projects. Find out how to access here.

The platform gives access to state-of-the-art cryo-EM equipment for structure determination projects using the latest technology and methods. The platform hosts a FEI Titan Krios G3 equipped with a phase plate and a Quantum-K3 camera and a 200 kV FEI Talos Arctica with an electron counting Falcon 3 camera. Both microscopes are equipped with an automatic sample loading system and configured for automatic data acquisition.

Experts are on hand to help and support researchers during microscope handling, data acquisition and optimisation of imaging conditions.

Thanks to a continuous test program with Thermo Fisher Scientific, we ensure the microscopes have the latest hardware and software features.

The Cryo-Electron Microscopy Service Platform at EMBL Heidelberg is now offering remote service to all interested users, including the COVID-19-related projects (single-particle analysis and cryo-electron tomography). Due to the current situation, we are unfortunately not able to host you in person, but we are happy to receive your proposals and your samples per post, and perform measurements for you.