{"id":784,"date":"2024-03-25T11:10:51","date_gmt":"2024-03-25T11:10:51","guid":{"rendered":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/?page_id=784"},"modified":"2024-07-03T12:31:40","modified_gmt":"2024-07-03T12:31:40","slug":"pesticide-microbiome","status":"publish","type":"page","link":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/projects\/pesticide-microbiome\/","title":{"rendered":"Effects of pesticides on human gut microbiota"},"content":{"rendered":"\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p class=\"vf-lede\">Exploring the impact of 30 commonly used pesticides on gut health and metabolism.<\/p>\n<!--\/vf-lede-->\n\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"vf-figure wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"563\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/05\/GutMicrobiome_Composition_1000x563px.jpg\" alt=\"\" class=\"wp-image-1520\" style=\"width:673px;height:auto\" srcset=\"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/05\/GutMicrobiome_Composition_1000x563px.jpg 1000w, https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/05\/GutMicrobiome_Composition_1000x563px-300x169.jpg 300w, https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/05\/GutMicrobiome_Composition_1000x563px-768x432.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><figcaption class=\"vf-figure__caption\">Credit: adobestock.com<\/figcaption><\/figure>\n\n\n\n<p class=\"vf-text--body vf-text-body--5\"><\/p>\n\n\n\n<p>Pesticides are a threat to human health through agricultural work and food chain exposures that reach human populations geographically distant from agricultural sites. Oral exposure through food intake suggests possible interactions with the gut microbiome. Brazil is the third largest exporter of agricultural products in the world with 474 new pesticides approved in 2019. In collaboration with Juliana Peroboli at UNIFESP, Brazil, this project will explore the impact of 30 commonly used pesticides on the human gut microbiota, employing metabolomics measurements and 16S-rRNA sequencing of ex-vivo microbiota cultures to determine impacts on microbiome community composition and on microbiome-mediated pesticide metabolism.<\/p>\n\n\n\n<p><\/p>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<h3 class=\"wp-block-heading\"><strong>Project Lead<\/strong><\/h3>\n\n\n<div class=\"vf-content-hub-html\" data-cache=\"ef319482\">\n      <!-- Generated by: http:\/\/content.embl.org\/api\/v1\/pattern.html?filter-content-type=person&amp;filter-field-contains%5Bfield_person_full_name%5D=michael%20zimmermann&amp;filter-fields-empty=field_person_visible_internally&amp;filter-ref-entity%5Bfield_person_positions%5D%5Btitle%5D=&amp;filter-ref-entity%5Bfield_person_positions%5D%5Bfield_position_primary%5D=1&amp;hide%5Bteam%2Cemail%2Cphones%2Cmobile%2Corcid%5D=1&amp;limit=1&amp;pattern=vf-profile-inline -->\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"88612\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60031476.jpg?itok=XXhmnt8h\" alt=\"image of Michael Zimmermann\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/michael-zimmermann\" class=\"vf-profile__link\">Michael Zimmermann<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Group Leader\n        <\/p>\n      \n      \n      \n      \n      \n      \n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/88612\/88612\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n  <\/div>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":0,"parent":161,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-title-left-aligned.php","meta":{"_acf_changed":false,"footnotes":""},"embl_taxonomy":[],"class_list":["post-784","page","type-page","status-publish","hentry"],"acf":[],"embl_taxonomy_terms":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages\/784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/comments?post=784"}],"version-history":[{"count":15,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages\/784\/revisions"}],"predecessor-version":[{"id":2403,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages\/784\/revisions\/2403"}],"up":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages\/161"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/media?parent=784"}],"wp:term":[{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/embl_taxonomy?post=784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}