{"id":662,"date":"2024-03-22T17:23:37","date_gmt":"2024-03-22T17:23:37","guid":{"rendered":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/?page_id=662"},"modified":"2024-07-03T11:24:52","modified_gmt":"2024-07-03T11:24:52","slug":"exposures-in-the-gwas-catalog","status":"publish","type":"page","link":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/projects\/exposures-in-the-gwas-catalog\/","title":{"rendered":"Exposures in the GWAS Catalog"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"vf-grid__col--span-2\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p class=\"vf-lede\">Enhancing the GWAS catalog to enable searching for exposure assocations<\/p>\n<!--\/vf-lede-->\n\n\n\n\n<figure class=\"vf-figure wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"614\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/06\/HE_Website_GWAS-1024x614.jpg\" alt=\"\" class=\"wp-image-1607\" srcset=\"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/06\/HE_Website_GWAS-1024x614.jpg 1024w, https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/06\/HE_Website_GWAS-300x180.jpg 300w, https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/06\/HE_Website_GWAS-768x461.jpg 768w, https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/06\/HE_Website_GWAS-1536x922.jpg 1536w, https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-content\/uploads\/2024\/06\/HE_Website_GWAS-2048x1229.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p>The GWAS Catalog is a comprehensive public repository of all published genome-wide association studies (GWAS). Significant associations are extracted from publications and authors may additionally submit full genome-wide summary statistics files to enable a wider range of downstream analyses. Data is QC\u2019d, structured and richly annotated to ensure it is Findable, Accessible, Interoperable and Reusable (FAIR). This project will enhance the GWAS Catalog for GxE research through analysing all existing traits in the catalogue and annotating with searchable ontology terms into phenotype and exposure.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<h3 class=\"wp-block-heading\"><strong>Project Leads<\/strong><\/h3>\n\n\n<div class=\"vf-content-hub-html\" data-cache=\"fabb39c2\">\n      <!-- Generated by: http:\/\/content.embl.org\/api\/v1\/pattern.html?filter-content-type=person&amp;filter-field-contains%5Bfield_person_full_name%5D=Laura%20Harris&amp;filter-fields-empty=field_person_visible_internally&amp;filter-ref-entity%5Bfield_person_positions%5D%5Btitle%5D=&amp;filter-ref-entity%5Bfield_person_positions%5D%5Bfield_position_primary%5D=1&amp;hide%5Bteam%2Cemail%2Cphones%2Cmobile%2Corcid%5D=1&amp;limit=1&amp;pattern=vf-profile-inline -->\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"87220\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60025554.jpg?itok=6JILGN4D\" alt=\"image of Laura Harris\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.ebi.ac.uk\/people\/person\/laura-harris\" class=\"vf-profile__link\">Laura Harris<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          GWAS Catalog Coordinator\n        <\/p>\n      \n      \n      \n              \n              \n      \n                                      \n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/87220\/87220\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n  <\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Related Services:<\/strong><\/h3>\n\n\n\n<article class=\"vf-card vf-card--brand vf-card--striped vf-u-margin__bottom--800\" default>\n  \n  <div class=\"vf-card__content | vf-stack vf-stack--400\">\n          <h3 class=\"vf-card__heading\">\n                  <a class=\"vf-card__link\" href=\"https:\/\/www.ebi.ac.uk\/gwas\/\" target=\"\">\n        \n        GWAS Catalog\n                  <svg aria-hidden=\"true\" class=\"vf-card__heading__icon | vf-icon vf-icon-arrow--inline-end\" width=\"1em\" height=\"1em\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n            <path d=\"M0 12c0 6.627 5.373 12 12 12s12-5.373 12-12S18.627 0 12 0C5.376.008.008 5.376 0 12zm13.707-5.209l4.5 4.5a1 1 0 010 1.414l-4.5 4.5a1 1 0 01-1.414-1.414l2.366-2.367a.25.25 0 00-.177-.424H6a1 1 0 010-2h8.482a.25.25 0 00.177-.427l-2.366-2.368a1 1 0 011.414-1.414z\" fill=\"currentColor\" fill-rule=\"nonzero\"><\/path>\n          <\/svg>\n        <\/a>\n              <\/h3>\n    \n    \n      <\/div>\n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":0,"parent":161,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-title-left-aligned.php","meta":{"_acf_changed":false,"footnotes":""},"embl_taxonomy":[],"class_list":["post-662","page","type-page","status-publish","hentry"],"acf":[],"embl_taxonomy_terms":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages\/662","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/comments?post=662"}],"version-history":[{"count":12,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages\/662\/revisions"}],"predecessor-version":[{"id":2223,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages\/662\/revisions\/2223"}],"up":[{"embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/pages\/161"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/media?parent=662"}],"wp:term":[{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/about\/info\/human-ecosystems\/wp-json\/wp\/v2\/embl_taxonomy?post=662"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}