{"id":1209,"date":"2021-03-09T13:54:07","date_gmt":"2021-03-09T13:54:07","guid":{"rendered":"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/?post_type=vf_event&#038;p=1209"},"modified":"2021-11-24T13:41:09","modified_gmt":"2021-11-24T13:41:09","slug":"can21-01","status":"publish","type":"vf_event","link":"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/events\/can21-01\/","title":{"rendered":"Cancer genomics"},"content":{"rendered":"\n<div class=\"vf-tabs\"><ul class=\"vf-tabs__list\" data-vf-js-tabs=\"true\"><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2\" data-vf-js-location-nearest-activation-target=\"\">Overview<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-311a4dae-4712-45c4-bb7c-83f569003b70\" data-vf-js-location-nearest-activation-target=\"\">Speakers<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-3ec32bc7-85db-476f-962b-ceac3f6f67b7\" data-vf-js-location-nearest-activation-target=\"\">Programme<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-e47404fd-83e1-4110-b6cb-407254ce29c5\" data-vf-js-location-nearest-activation-target=\"\">Practical Information<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-dce3141a-e52c-4a7f-b1e1-71a8ad937c0b\" data-vf-js-location-nearest-activation-target=\"\">Sponsors<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-3cf8d6bc-00cb-47ad-99dc-0963e576f4e0\" data-vf-js-location-nearest-activation-target=\"\">Pre-conference webinars<\/a><\/li><\/ul><div class=\"vf-tabs-content\" data-vf-js-tabs-content=\"true\">\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2\"><h2 class=\"vf-u-sr-only\">Overview<\/h2>\n<p><\/p>\n\n\n\n<p><strong>EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic. We are delighted to announce that this conference is going virtual and invite you to join us online.<\/strong><\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Conference Overview<\/h2>\n\n\n\n<p>This conference will provide an opportunity to learn about and keep up to date with the rapidly progressing area of cancer genomics. It will cover presentations from cancer genome projects, the areas of cancer functional genomics, systems biology, cancer immunogenomics and epigenomics, cancer mouse models and the translation and clinical impact of obtained scientific results. The meeting will bring together leading scientists from across these areas for a unique opportunity to interact and stimulate further integration of these efforts.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Session Topics<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Mutation and clonal selection in normal tissues<\/li><li>Genomic instability and mutational processes<\/li><li>Cancer evolution and drivers<\/li><li>Emerging technologies in cancer genomics<\/li><li>Cancer ecosystems, microenvironment and immunogenomics<\/li><li>Cancer genome medicine<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">What past participants say about the conference:<\/h3>\n\n\n\n<p>&#8220;<em>EMBL provided a wonderful opportunity for the exchange and application of new ideas within the OMICs cancer research. A great conference!<\/em>&#8221; &#8211; Angelica Boldt, Postgraduate Program in Genetics, Department of Genetics, Federal University of Paran\u00e1 (UFPR), Argentina<\/p>\n\n\n\n<p>&#8220;<em>This is the third time I have attended this conference. I keep coming back because of the quality of work presented, the expectation that presenters discuss their latest findings and the meeting having the optimal number of attendees.<\/em>&#8221; &#8211; Sean Grimmond, University of Melbourne, Australia<\/p>\n\n\n\n<p><\/p>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-311a4dae-4712-45c4-bb7c-83f569003b70\"><h2 class=\"vf-u-sr-only\">Speakers<\/h2>\n<h2 class=\"wp-block-heading\">Keynote Speaker<\/h2>\n\n\n\n<div class=\"embl-grid\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n            <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/dev.assets.emblstatic.net\/vf\/v2.0.0-alpha.6\/assets\/vf-summary\/assets\/vf-icon--avatar.svg\" > \n    \n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.sanger.ac.uk\/person\/campbell-peter\/\" target=\"_self\" class=\"vf-profile__link\">Peter Campbell<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Wellcome Sanger Institute            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                UK            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Speakers<\/h2>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Carter-new.jpg\" class=\"vf-profile__image\" alt=\"Hannah Carter\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/medschool.ucsd.edu\/som\/medicine\/divisions\/med-genetics\/research\/carter-lab\/Pages\/default.aspx\" target=\"_self\" class=\"vf-profile__link\">Hannah Carter<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                University of California            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                San Diego            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                USA            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Cuppen-new.jpg\" class=\"vf-profile__image\" alt=\"Edwin Cuppen\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.umcutrecht.nl\/en\/Research\/Other-research\/Center-for-Molecular-Medicine\/Section-Genetics\/Cuppen\" target=\"_self\" class=\"vf-profile__link\">Edwin Cuppen<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                UMC Utrecht            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                The Netherlands            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Curtis-new.jpg\" class=\"vf-profile__image\" alt=\"Christina Curtis\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"http:\/\/med.stanford.edu\/curtislab.html\" target=\"_self\" class=\"vf-profile__link\">Christina Curtis<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Stanford University            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                USA            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Gerstung-new.jpg\" class=\"vf-profile__image\" alt=\"Moritz Gerstung\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.ebi.ac.uk\/research\/gerstung\" target=\"_self\" class=\"vf-profile__link\">Moritz Gerstung<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                EMBL-EBI Hinxton            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                UK            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Heyn-new.jpg\" class=\"vf-profile__image\" alt=\"Holger Heyn\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.cnag.crg.eu\/holger-heyn\" target=\"_self\" class=\"vf-profile__link\">Holger Heyn<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Centre for Genomic             <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Regulation (CNAG-CRG)            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Spain            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Imielinski-new.jpg\" class=\"vf-profile__image\" alt=\"Marcin Imielinski\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"http:\/\/www.mskilab.org\/\" target=\"_self\" class=\"vf-profile__link\">Marcin Imieli\u0144ski<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Weill Cornell Medicine            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                USA            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Jabado-new.jpg\" class=\"vf-profile__image\" alt=\"Nada Jabado\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.jabadolab.com\/\" target=\"_self\" class=\"vf-profile__link\">Nada Jabado<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                McGill University            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Canada            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/01\/Korbel-NEW.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"http:\/\/www.korbel.embl.de\/?_ga=2.51729449.1672537756.1614600592-1626069216.1538645382\" target=\"_self\" class=\"vf-profile__link\">Jan Korbel<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                EMBL Heidelberg            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Germany            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Landau-new.jpg\" class=\"vf-profile__image\" alt=\"Dan A. Landau\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.landaulab.org\/\" target=\"_self\" class=\"vf-profile__link\">Dan Landau<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Weill Cornell Medical            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                College            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                USA            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"75\" height=\"75\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/04\/loh_headshot_2_1_0.jpg\" class=\"vf-profile__image\" alt=\"Po-Ru Loh\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"http:\/\/statgen.hms.harvard.edu\/\" target=\"_self\" class=\"vf-profile__link\">Po-Ru Loh<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Harvard Medical School            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                USA            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Lopez-Bigas-NEW1.jpg\" class=\"vf-profile__image\" alt=\"N\u00faria L\u00f3pez-Bigas\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.irbbarcelona.org\/en\/research\/biomedical-genomics\" target=\"_self\" class=\"vf-profile__link\">N\u00faria L\u00f3pez-Bigas<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Institute for Research            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                in Biomedicine            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Spain            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/01\/Ogawa-NEW.jpg\" class=\"vf-profile__image\" alt=\"Seishi Ogawa\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"http:\/\/www.med.kyoto-u.ac.jp\/en\/organization-staff\/research\/doctoral_course\/r-006\/\" target=\"_self\" class=\"vf-profile__link\">Seishi Ogawa<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Kyoto University            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Japan            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Papaemmanuil-new1.jpg\" class=\"vf-profile__image\" alt=\"Elli Papaemmanuil\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.mskcc.org\/research-areas\/labs\/elli-papaemmanuil\" target=\"_self\" class=\"vf-profile__link\">Elli Papaemmanuil<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Memorial Sloan Kettering             <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Cancer Center            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                USA            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Rahbari-new.jpg\" class=\"vf-profile__image\" alt=\"Raheleh Rahbari\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.sanger.ac.uk\/group\/rahbari-group\/\" target=\"_self\" class=\"vf-profile__link\">Raheleh Rahbari<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Wellcome Sanger Institute            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                UK            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n            <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/dev.assets.emblstatic.net\/vf\/v2.0.0-alpha.6\/assets\/vf-summary\/assets\/vf-icon--avatar.svg\" > \n    \n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/k-ris.keio.ac.jp\/html\/100001725_en.html\" target=\"_self\" class=\"vf-profile__link\">Toshiro Sato<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Keio University            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Japan            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/Supek-new.jpg\" class=\"vf-profile__image\" alt=\"Fran Supek\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.irbbarcelona.org\/en\/research\/genome-data-science\" target=\"_self\" class=\"vf-profile__link\">Fran Supek<\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Institute for Research             <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                in Biomedicine            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Spain            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Scientific Organisers<\/h2>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/01\/Korbel-NEW.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www-korbel.embl.de\/?_ga=2.180623527.1411930343.1610703567-987632742.1610703567\" target=\"_self\" class=\"vf-profile__link\">Jan Korbel <\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                EMBL Heidelberg            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Germany            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/01\/Lopez-Bigas-NEW.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.irbbarcelona.org\/en\/research\/biomedical-genomics\" target=\"_self\" class=\"vf-profile__link\">N\u00faria L\u00f3pez-Bigas <\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Institute for Research            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                in Biomedicine            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Spain            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/01\/Ogawa-NEW.jpg\" class=\"vf-profile__image\" alt=\"Seishi Ogawa\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.med.kyoto-u.ac.jp\/en\/organization-staff\/research\/doctoral_course\/r-006\/\" target=\"_self\" class=\"vf-profile__link\">Seishi Ogawa <\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Kyoto University            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Japan            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/01\/Papaemmanuil-new.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    <a href=\"https:\/\/www.mskcc.org\/research-areas\/labs\/elli-papaemmanuil\" target=\"_self\" class=\"vf-profile__link\">Elli Papaemmanuil <\/a>\n            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Memorial Sloan Kettering             <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Cancer Center            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                USA            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Conference Organiser<\/h2>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"115\" height=\"135\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/01\/heck_maryann-1.jpg\" class=\"vf-profile__image\" alt=\"\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    Maryann Heck            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                EMBL Heidelberg            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Germany            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--block | vf-u-margin__bottom--400\">\n\n    <img decoding=\"async\" width=\"155\" height=\"175\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/03\/chris-stocks.jpg\" class=\"vf-profile__image\" alt=\"Chris Stocks\" loading=\"lazy\" itemprop=\"image\" \/>\n    <h3 class=\"vf-profile__title\" style=\"text-align: center;\">\n                    Chris Stocks            <\/h3>\n    \n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                EMBL Heidelberg            <\/p>\n                <p class=\"vf-profile__text\" style=\"text-align: center;\">\n                Germany            <\/p>\n    \n    \n      \n\n    \n<\/article>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<p><\/p>\n<\/div><\/div>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-3ec32bc7-85db-476f-962b-ceac3f6f67b7\"><h2>Programme<\/h2>\n<p>Got something to say? Tweet it! #EMBLCanGen<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The virtual conference includes live-streamed invited speaker talks and live-streamed selected short talks with live Q&amp;A sessions after each talk as well as meet the speaker sessions.<\/li><li><strong>All digital poster presenters are encouraged to upload a recorded flash talk <\/strong><br><strong>or narration with their digital poster and to schedule video calls during poster session times.<\/strong><\/li><li>Information on the live stream and access to the discussion platform and digital posters will be provided 1 week before the start of the event.<\/li><\/ul>\n\n\n\n<p>All times in the programme below are shown as the time in <strong>Europe\/Berlin.<\/strong><\/p>\n\n\n\n<p>To find out the equivalent time zone in your location, enter Berlin, the programme time and your city into the&nbsp;<a href=\"https:\/\/dateful.com\/time-zone-converter?t=1114&amp;tz2=Berlin-Germany\" target=\"_blank\" rel=\"noreferrer noopener\">Time Zone Converter<\/a>.<\/p>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nDay 1 \u2013 Monday 22 November 2021<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<figure class=\"wp-block-table\"><table><thead><tr><th><strong>Time<\/strong><\/th><th><strong>Speaker<\/strong><\/th><\/tr><\/thead><tbody><tr><td>12:00 &#8211;  12:50<\/td><td><p><strong>Pre-conference webinars:<\/strong><\/p><ul><li><strong>Precision Medicine meets immuno-oncology \u2013 innovative biomarkers and beyond<\/strong> by Bristol-Myers Squibb<\/li><\/ul><ul><li><strong>DNA methylation in biofluids: from genome-wide studies to targeted approaches<\/strong> by Diagenode<\/li><\/ul>(abstracts are available in <strong>Pre-conference webinars<\/strong> tab)<\/td><\/tr><tr><td>13:00 &#8211; 13:50<\/td><td><p><strong>Pre-conference webinars:<\/strong><\/p><ul><li><strong>3D Genome Analysis Identifies Therapeutic Targets in Pediatric Brain Cancer<\/strong> by Arima Genomics<\/li><\/ul><ul><li><strong>Structural and functional heterogeneity in the spatial organization of glioblastoma patient genomes<\/strong> by Dovetail Genomics<\/li><\/ul>(abstracts are available in <strong>Pre-conference webinars<\/strong> tab)<\/td><\/tr><tr><td>14:00 &#8211; 14:10<\/td><td><strong>Opening remarks<\/strong><\/td><\/tr><tr><td>14:10 &#8211; 15:25<\/td><td><strong>Session 1:<br>Mutation and clonal selection in normal tissues<\/strong><\/td><\/tr><tr><td>14:10 &#8211; 14:40<\/td><td><strong>The mutational landscape and clonal dynamics of Human Somatic and Germline cells<\/strong><br>Raheleh Rahbari &#8211; Wellcome Sanger Institute, UK<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>14:40 &#8211; 14:55<\/td><td><strong>Somatic Mutations in The Ageing Brain<\/strong><br>Luke Harvey &#8211; Welcome Trust Sanger Institute, UK<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>14:55 &#8211; 15:25<\/td><td><strong>Monogenic and polygenic inheritance become instruments for clonal selection<\/strong><br>Po-Ru Loh &#8211; Harvard Medical School, USA<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>15:25 &#8211; 15:40<\/td><td>Break<\/td><\/tr><tr><td>15:40 &#8211; 16:25<\/td><td><strong>Keynote:<\/strong> <strong>Talk title to be announced<\/strong><br>Peter Campbell &#8211; Wellcome Sanger Institute, UK<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>16:25 &#8211; 17:00<\/td><td><strong>Meet the speakers from Session 1<\/strong><\/td><\/tr><tr><td>17:00 &#8211; 18:00<\/td><td><strong>Poster Session 1<br>(live chats and video calls with poster presenters with last names A-L)<\/strong><\/td><\/tr><tr><td>18:00 &#8211; 18:15<\/td><td>Break<\/td><\/tr><tr><td>18:15 &#8211; 20:15<\/td><td><strong>Session 2:<br>Genomic instability and mutational processes<\/strong><\/td><\/tr><tr><td>18:15 &#8211; 18:45<\/td><td><strong>Patterns in local mutation density in cancer genomes<\/strong><br>Fran Supek &#8211; Institute for Research in Biomedicine, Spain<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>18:45 &#8211; 19:00<\/td><td><strong>Re-running cancer evolution in vivo: a high-resolution multi-omics approach<\/strong><br>Sarah Aitken &#8211; University of Cambridge, UK<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>19:00 &#8211; 19:30<\/td><td><strong>In silico saturation mutagenesis of cancer genes<\/strong><br>Nuria Lopez-Bigas &#8211; Institute for Research in Biomedicine, Spain<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong>  <\/td><\/tr><tr><td>19:30 &#8211; 19:45<\/td><td><strong>Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients<\/strong><br>Jurrian de Kanter &#8211; Princess M\u00e1xima Center for Pediatric Oncology, The Netherlands<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>19:45 &#8211; 20:15<\/td><td><strong>Haplotype-aware single-cell multiomics uncovers functional effects of somatic structural variation<\/strong><br>Jan Korbel &#8211; EMBL Heidelberg, Germany<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong>  <\/td><\/tr><tr><td>20:15 &#8211; 20:25<\/td><td>Break<\/td><\/tr><tr><td>20:25 &#8211; 20:55<\/td><td><strong>Meet the speakers from Session 2 <\/strong><\/td><\/tr><tr><td>20:55 &#8211; 21:30<\/td><td><strong>Virtual Speed Networking<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nDay 2 \u2013 Tuesday 23 November 2021<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<figure class=\"wp-block-table\"><table><thead><tr><th><strong>Time <\/strong><\/th><th><strong>Speaker<\/strong><\/th><\/tr><\/thead><tbody><tr><td>13:30 &#8211; 13:50 <\/td><td> <strong>Industry session<\/strong> <\/td><\/tr><tr><td>14:00 &#8211; 16:30<\/td><td><strong>Session 3: Cancer evolution and drivers<\/strong><\/td><\/tr><tr><td>14:00 &#8211; 14:30<\/td><td><strong>Molecular classification and risk stratification of colorectal cancer<\/strong><br>Seishi Ogawa &#8211;  Kyoto University, Japan<br> <strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong>  <\/td><\/tr><tr><td>14:30 &#8211; 14:45<\/td><td><strong>Discerning patterns of evolution during progression and metastatic spread in high risk neuroblastoma<\/strong><br>Gunes Gundem &#8211; Memorial Sloan Kettering Cancer Center, USA<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>14:45 &#8211; 15:00<\/td><td><strong>ASCAT.sc: a generic framework for copy-number calling<\/strong><br>Maxime Tarabichi &#8211; Universit\u00e9 Libre de Bruxelles (ULB), Belgium<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>15:00 &#8211; 15:30<\/td><td><strong>Genotype to phenotype mapping of tumorigenesis at single cell resolution<\/strong><br>Christina Curtis &#8211;  Stanford University, USA<br><strong>LIVE STREAM ONLY<\/strong> <\/td><\/tr><tr><td>15:30 &#8211; 15:45<\/td><td>Break<\/td><\/tr><tr><td>15:45 &#8211; 16:15<\/td><td><strong>Stalled development through altered epigenetic states <\/strong><br><strong>at the root of oncohistone pathogenicity<\/strong><br>Nada Jabado &#8211;  McGill University, Canada<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>16:15 &#8211; 16:30<\/td><td><strong>Reconstructing Chromothriptic Chromosomes in Oesophageal Adenocarcinomas<\/strong><br>Jannat Ijaz &#8211; Wellcome Trust Sanger Institute, UK<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>16:30- 17:05<\/td><td><strong>Meet the speakers from Session 3<\/strong><\/td><\/tr><tr><td>17:05 &#8211; 18:05<\/td><td><strong>Poster Session 2<br>(live chats and video calls with poster presenters with last names M-Z)<\/strong><\/td><\/tr><tr><td>18:05 &#8211; 18:20<\/td><td>Break<\/td><\/tr><tr><td>18:20 &#8211; 19:50<\/td><td><strong>Session 4:<br>Emerging technologies in cancer genomics<\/strong><\/td><\/tr><tr><td>18:20 &#8211; 18:50<\/td><td><strong>Pathognomonic long molecule footprints of backup repair pathways in homologous recombination deficient cancers<\/strong><br>Marcin Imilienski &#8211; Weill Cornell Medicine, USA<br> <strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong>  <\/td><\/tr><tr><td>18:50 &#8211; 19:05<\/td><td><strong>Exploiting immunity of hepatocellular carcinoma (HCC) to improve treatment of patients<\/strong><br>Domitille Chalopin-Fillot &#8211; Universit\u00e9 de Bordeaux, France<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>19:05 &#8211; 19:35<\/td><td><strong>Single-cell and spatially-resolved <\/strong><br><strong>tumor immune microenvironments<\/strong><br>Holger Heyn &#8211; Centre for Genomic Regulation (CNAG-CRG), Spain<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>19:35 &#8211; 19:50<\/td><td><strong>Modeling human clonal hematopoiesis in vitro<\/strong><br>Franziska Briest &#8211; Universit\u00e4ts Medizin Berlin, Germany<br><strong>LIVE STREAM ONLY<\/strong><\/td><\/tr><tr><td>19:50 &#8211; 20:00<\/td><td>Break<\/td><\/tr><tr><td>20:00 &#8211; 20:30<\/td><td><strong>Meet the speakers from Session 4<\/strong><\/td><\/tr><tr><td>20:30 &#8211; 21:30<\/td><td><strong>Bar Mixer<br><\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nDay 3 &#8211; Wednesday 24 November 2021<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<figure class=\"wp-block-table\"><table><thead><tr><th><strong>Time<\/strong><\/th><th><strong>Speaker<\/strong><\/th><\/tr><\/thead><tbody><tr><td>14:00 &#8211; 16:30<\/td><td><strong>Session 5:<br>Cancer ecosystems, microenvironment and <\/strong><br><strong>immunogenomics<\/strong><\/td><\/tr><tr><td>14:00 &#8211; 14:30<\/td><td><strong>Understanding of cancer genotype-phenotype association <\/strong><br><strong>using organoid technology<\/strong><br>Toshiro Sato &#8211;  Keio University, Japan<br><strong> <strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong>  <\/strong><\/td><\/tr><tr><td>14:30 &#8211; 14:45<\/td><td><strong>The relationship of germline risk to somatic EGFR mutation in lung cancer<\/strong><br>Matthew Meyerson &#8211; Dana-Farber Cancer Institute, USA<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>14:45 &#8211; 15:00<\/td><td><strong>The impact and prevalence of genetic immune escape in primary and metastatic cancer<\/strong><br>Francisco Mart\u00ednez-Jim\u00e9nez &#8211; UMC Utrecht, The Netherlands<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>15:00 &#8211; 15:30<\/td><td><strong>Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states<\/strong><br>Dan Landau &#8211;  Weill Cornell Medical College, USA<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>15:30 &#8211; 15:45<\/td><td>Break<\/td><\/tr><tr><td>15:45 &#8211; 16:15<\/td><td><strong>Germline immune variants influence tumor <\/strong><br><strong>immunotherapy outcomes<\/strong><br>Hannah Carter &#8211;  University of California, San Diego, USA<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong><\/td><\/tr><tr><td>16:15 &#8211; 16:30<\/td><td><strong>The somatic mutational landscape of normal tissues in chemotherapy-treated cancer patients<\/strong><br>Ellie Dunstone &#8211; Sanger Institute, UK<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>16:30 &#8211; 17:05<\/td><td><strong>Meet the speakers from Session 5<\/strong><\/td><\/tr><tr><td>17:05 &#8211; 17:20<\/td><td>Break<\/td><\/tr><tr><td>17:20 &#8211; 19:20<\/td><td><strong>Session 6:<br>Cancer genome medicine<\/strong><\/td><\/tr><tr><td>17:20 &#8211; 17:50<\/td><td><strong>Talk title to be announced<\/strong><br>Elli Papaemanouil &#8211; Memorial Sloan Kettering Cancer Center, USA<br><strong>LIVE STREAM ONLY<\/strong> <\/td><\/tr><tr><td>17:50 &#8211; 18:05<\/td><td><strong>A clinical-molecular and personalized risk scoring system for patients with myelodysplastic syndromes<\/strong><br>Elsa Bernard &#8211; Memorial Sloan Kettering Cancer Center, USA<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>18:05 &#8211; 18:35<\/td><td><strong>Spatial genomics maps the structure, character and evolution of cancer clones<\/strong><br>Moritz Gerstung &#8211; EMBL-EBI Hinxton, UK<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong>  <\/td><\/tr><tr><td>18:35 &#8211; 18:50<\/td><td><strong>Mutagenic effects of chemotherapy in secondary malignancies and normal cells in pediatric cancer patients<\/strong><br>Axel Rosendahl Huber &#8211; Princess M\u00e1xima Center for Pediatric Oncology and Oncode Institute, The Netherlands<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong>   <\/td><\/tr><tr><td>18:50 &#8211; 19:20<\/td><td><strong>Understanding mutational landscapes in metastatic cancer<\/strong><br>Edwin Cuppen &#8211; UMC Utrecht, The Netherlands<br><strong>AVAILABLE ON DEMAND AFTER LIVE STREAM<\/strong> <\/td><\/tr><tr><td>19:20 &#8211; 19:30<\/td><td><strong>Closing remarks<\/strong><\/td><\/tr><tr><td>19:30 &#8211; 20:00<\/td><td><strong>Meet the speakers from Session 6<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n<\/div>\n<\/details>\n\n\n\n<p><\/p>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-e47404fd-83e1-4110-b6cb-407254ce29c5\"><h2>Practical Information<\/h2>\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nRegistration Fees and Abstract Submission<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<p><strong>Registration Fees<\/strong>&nbsp;(include access to all of the talks, digital poster sessions and online group discussions, and help us cover our costs to run the event. For further information please refer to the&nbsp;<a href=\"https:\/\/www.embl.de\/training\/events\/info_participants\/faqs\/faqs_participants\/index.html#FAQ_PA_reg8#FAQ_PA_reg8\">FAQ page<\/a>):<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-regular\"><table><tbody><tr><td><strong>Academia<\/strong><\/td><td>190 Euro<\/td><\/tr><tr><td><strong>PhD Student<\/strong><\/td><td>140 Euro<\/td><\/tr><tr><td><strong>Industry<\/strong><\/td><td>240 Euro<\/td><\/tr><tr><td><strong>EMBL Staff<\/strong><\/td><td><a target=\"_blank\" href=\"http:\/\/intranet.embl.de\/training\/cco\/staff\/index.html\" rel=\"noreferrer noopener\">Intranet access<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Accredited journalists may be eligible to register for a complimentary registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact&nbsp;<a href=\"https:\/\/www-db.embl.de\/EMBLPersonGroup-PersonPicture\/MailForm\/?recipient=CP-60020037&amp;mailSubject=Cancer%20Genomics%20&amp;_ga=2.191520994.970717781.1618209150-849272964.1538049481\">Maryann Heck<\/a>&nbsp;for more information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"confirmation\">Confirmation and Payment<\/h2>\n\n\n\n<p>Registration will be on a first-come first-served basis. Your place can only be confirmed after payment of the registration fee.<br>Types of payments accepted are international bank transfers and credit card payments.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"abstract\">Abstract submission<\/h2>\n\n\n\n<p>Only registered participants are eligible to submit an abstract. We only accept online abstract submissions.<br><br>After you have logged in and successfully registered, you will receive an email asking you to submit your abstract.&nbsp; Click on the link provided and enter your abstract in the text box provided. Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering.<\/p>\n\n\n\n<p>When submitting your abstract you can also apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.<\/p>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nFinancial Assistance<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<h2 class=\"wp-block-heading\">Financial Assistance<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Registration Fee Waivers<\/h3>\n\n\n\n<p>All academic and student registrants are invited to apply for a registration fee waiver, provided by the EMBL Advanced Training Centre Corporate Partnership Programme. The registration fee waiver covers the registration sum that you have paid to attend the meeting. Conference participants are not required to pre-pay the registration fee to be selected for a fee waiver for a virtual meeting. If you have already paid the registration fee and are awarded a fee waiver, it will be reimbursed after the meeting. Course participants are required to pay the course fee in advance, which will then be reimbursed after the recipient has attended the course.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Childcare Grants<\/h3>\n\n\n\n<p>For participants and speakers with childcare responsibilities there is the possibility to apply for a grant, provided by the EMBL Advanced Training Centre Corporate Partnership Programme, to offset childcare costs incurred when participating at a virtual event. Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver. Please note that priority will be given to early stage researchers. Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received. Attendance at the event is required in order to be eligible to receive the reimbursement. In order to apply for this grant, you must be registered by the abstract submission deadline.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Application<\/strong><\/h3>\n\n\n\n<p>Applications for financial assistance can be submitted via the submission portal* (for the submission of abstracts for conferences or the submission of motivation letters for courses) by completing the Financial Assistance Application Section (underneath the section for entering abstract\/motivation letter information). The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course.<\/p>\n\n\n\n<p>For conferences, if you are not submitting an abstract, you can still apply for financial assistance in the submission portal. Take a look at the <a href=\"https:\/\/www.embl.de\/training\/events\/info_participants\/fellowships\/FA_instructions.pdf\">instructions for applying for financial assistance<\/a>.<\/p>\n\n\n\n<p>Note that priority will be given to those submitting an abstract to present at the conference. In your application you will be asked to answer questions regarding your motivation for applying, and, for registration fee waivers, the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.<\/p>\n\n\n\n<p>*For some events, applications for Childcare Grants will still be done by email. Information about the grant will be sent out shortly after the abstract\/motivation letter deadline. Please contact the event Conference Officer if you have any questions.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Selection<\/strong><\/h3>\n\n\n\n<p>The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses. Results will be announced approximately 3 \u2013 4 weeks before the event start date. Selection results do not impact your admission to the meeting. Registration fee waiver selection is based on your current work or study location, your motivation for applying, the reasons for needing financial support and the impact this event will have on your career. Childcare grants are allocated based on career stage, with priority given to early stage researchers.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Further details<\/strong><\/h3>\n\n\n\n<p>A list of external funding opportunities can be found&nbsp;<a href=\"https:\/\/www.embl.de\/training\/events\/info_participants\/fellowships\/external_funding_sources\/index.html\">here<\/a>, and information on attending a conference as an event reporter&nbsp;<a href=\"https:\/\/www.embl.de\/training\/events\/info_participants\/eventreporter\/index.php\">here<\/a>.<\/p>\n\n\n\n<p>For further information about financial assistance please refer to the&nbsp;<a href=\"https:\/\/www.embl.de\/training\/events\/info_participants\/faqs\/faqs_participants\/index.html#FAQ_PA_trav1\">FAQ page<\/a>.<\/p>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nVirtual Participation Guidelines<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<h2 class=\"wp-block-heading\" id=\"guidelines\">Guidelines<\/h2>\n\n\n\n<p>Please&nbsp;<strong>do<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Use the event-specific hashtag as communicated during the event for any related tweets<\/li><li>Tweet unless the speaker specifically says otherwise<\/li><li>Be mindful of unpublished data<\/li><li>Be respectful in tone and content<\/li><\/ul>\n\n\n\n<p>Please&nbsp;<strong>don&#8217;t<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Share Slack, live stream or poster session links with others<\/li><li>Broadcast the conference to unregistered participants<\/li><li>Capture, transmit or redistribute data presented at the meeting unless presenter gives explicit consent<\/li><li>Use offensive language in your posts<\/li><li>Engage in rudeness or personal attacks<\/li><\/ul>\n\n\n\n<p>Additional information can be found in our&nbsp;<a href=\"http:\/\/www.embo-embl-symposia.org\/info_participants\/codeofconduct\/index.php\" target=\"_blank\" rel=\"noreferrer noopener\">Code of Conduct<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"health\">Health and well-being<\/h2>\n\n\n\n<p>It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the events Slack workspace for you to enjoy during the event.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"questions\">How to ask questions<\/h2>\n\n\n\n<p>Questions during and after the talks can be asked in live streaming platform. The chair moderates the questions and shares them with the speaker. If time runs out or you think of a question later, you can use Slack to ask your questions in the dedicated session channels or via direct message.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"time\">Time zone<\/h2>\n\n\n\n<p>The programme is planned based on Central European Summer Time (CEST), unless otherwise stated. As many virtual participants are attending from around the world, we do our best to accomodate as many timezones as possible when creating the programme. Please take your time zone into consideration when planning your attendance.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"platforms\">Virtual event platforms<\/h2>\n\n\n\n<p>We are using a virtual event platform for this conference. More information about the platform will be shared ahead of the conference.<\/p>\n\n<\/div>\n<\/details>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-dce3141a-e52c-4a7f-b1e1-71a8ad937c0b\"><h2>Sponsors<\/h2>\n<p>&nbsp;<\/p>\n\n\n\n<p><strong>Gold sponsor<\/strong><\/p>\n\n\n\n<div class=\"vf-grid | vf-grid__col-3\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<figure class=\"vf-figure wp-block-image size-full\"><a href=\"https:\/\/www.bms.com\/\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"270\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/BMS_480X270.jpg\" alt=\"\" class=\"wp-image-17550\" srcset=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/BMS_480X270.jpg 480w, https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/BMS_480X270-300x169.jpg 300w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/a><\/figure>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p><strong>Silver sponsors<\/strong><\/p>\n\n\n\n<div class=\"vf-grid | vf-grid__col-4\"><div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<figure class=\"vf-figure wp-block-image size-full\"><a href=\"https:\/\/arimagenomics.com\/\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"270\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/Arima-Genomics_480X270.jpg\" alt=\"\" class=\"wp-image-17560\" srcset=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/Arima-Genomics_480X270.jpg 480w, https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/Arima-Genomics_480X270-300x169.jpg 300w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/a><\/figure>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<figure class=\"vf-figure wp-block-image size-full\"><a href=\"https:\/\/www.diagenode.com\/en\/\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"270\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/Diagenode_480X270.jpg\" alt=\"\" class=\"wp-image-16151\" srcset=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/Diagenode_480X270.jpg 480w, https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/10\/Diagenode_480X270-300x169.jpg 300w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/a><\/figure>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<figure class=\"vf-figure wp-block-image size-full\"><a href=\"https:\/\/dovetailgenomics.com\/\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"270\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/11\/Dovetail-Genomics-2_480X270.jpg\" alt=\"\" class=\"wp-image-17900\" srcset=\"https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/11\/Dovetail-Genomics-2_480X270.jpg 480w, https:\/\/www.embl.org\/about\/info\/course-and-conference-office\/wp-content\/uploads\/2021\/11\/Dovetail-Genomics-2_480X270-300x169.jpg 300w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/a><\/figure>\n\n\n\n<p><\/p>\n\n<\/div>\n<\/div>\n\n\n<div class=\"\"><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p><strong>Media Partnership<\/strong><\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"http:\/\/msb.embopress.org\/\" target=\"_blank\"><em>Molecular Systems Biology<\/em>, an EMBO Press journal<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/febs.onlinelibrary.wiley.com\/journal\/18780261\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Molecular Oncology<\/em>, a FEBSPRESS journal<\/a><\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/iubmb.org\/\" target=\"_blank\">International Union of Biochemistry and Molecular Biology<\/a><\/p>\n\n\n\n<p><a href=\"http:\/\/rsob.royalsocietypublishing.org\/\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Open Biology<\/em>, a Royal Society journal<\/a><\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p><strong>Sponsorship Opportunities<\/strong><\/p>\n\n\n\n<p>We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget.&nbsp;Discounts are available for companies sponsoring multiple events at EMBL Heidelberg.&nbsp;<a href=\"http:\/\/www.embl.de\/training\/events\/index.php?p_eventType=CON&amp;amp;p_outstation=HD&amp;amp;p_timeRange=FUTURE&amp;amp;submit=Show+Events\">View other conferences<\/a>, or contact&nbsp;<a href=\"mailto:sponsorship@embl.de\">sponsorship@embl.de<\/a>&nbsp;for further information.<\/p>\n\n\n\n<p>If you are interested in becoming a media partner of this event, please visit our&nbsp;<a href=\"http:\/\/www.embl.de\/training\/events\/sponsorship\/mediapartnerships\/\">media partnerships webpage<\/a>.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\"><p><a href=\"mailto:sponsoring@embl.de?subject=%5BCancer%20Genomics%5D%20Sponsorship%20Brochure&#038;body=Please%20kindly%20send%20me%20the%20sponsorship%20brochure%20for%20EMBL%20Conference:%20Cancer%20Genomics%20(22%20-%2024%20November%202021).\" class=\"vf-button vf-button--primary vf-button--pill\">Request a Sponsorship Brochure<\/a><\/p><\/div>\n\n\n\n<div class=\"vf-box vf-box--normal vf-box-theme--quaternary | vf-u-margin__bottom--400\">\n      <h3 class=\"vf-box__heading\">\n                Warning                  <\/h3> \n        <p class=\"vf-box__text\">EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name \u2018Judy Eastman\u2019 (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL\u2019s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.<\/p>\n<p class=\"vf-box__text\">Please also note that:<\/p>\n<ul>\n<li><span style=\"font-size: 12pt;\">EMBL never provides attendee lists for purchase. Any offers of such are fraudulent.<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">EMBL will never call or email you to ask for your credit card details or to request a payment.<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">All payments are on invoice.<\/span><\/li>\n<\/ul>\n<p class=\"vf-box__text\">Suspicious communications purportedly from, for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring@embl.de.<\/p>\n<\/div><\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-3cf8d6bc-00cb-47ad-99dc-0963e576f4e0\"><h2>Pre-conference webinars<\/h2>\n<p>Pre-symposium webinars will take place <strong>on Monday, 22 November 2021<\/strong><\/p>\n\n\n\n<p>Participation in this webinar is free of charge for registered conference attendees. The number of available places is limited (first come, first served). All registered conference attendees will receive an email with a registration link.<\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p><strong>12:00 \u2013 12:50<\/strong> <a href=\"https:\/\/dateful.com\/time-zone-converter?t=1114&amp;tz2=Berlin-Germany\" data-type=\"URL\" data-id=\"https:\/\/dateful.com\/time-zone-converter?t=1114&amp;tz2=Berlin-Germany\" target=\"_blank\" rel=\"noreferrer noopener\">(Berlin \/ Germany)<\/a><\/p>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nBristol-Myers Squibb: Precision Medicine meets immuno-oncology &#8211; innovative biomarkers and beyond<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<p><em><strong>Speaker: Dr. Christoph Benedikt Westphalen<\/strong>, Comprehensive Cancer Center M\u00fcnchen<\/em><\/p>\n\n\n\n<p>Immunotherapeutic interventions have revolutionised the treatment landscape in various malignancies.&nbsp;<\/p>\n\n\n\n<p>A more profound understanding of mechanisms underlying response and resistance to this class of agents will help to maximise patients\u2019 benefit.<\/p>\n\n\n\n<p>A range of potentially predictive biomarkers beyond PD-L1 and dMMR\/MSI are under investigation to help identify patients qualifying for immune therapy. Furthermore, additional modalities such as digital pathology, artificial intelligence and functional imaging are coming of age.&nbsp;<\/p>\n\n\n\n<p>This seminar aims to give an overview on emerging biomarkers and technologies supporting personalised approached in immunotherapy.&nbsp;<\/p>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nDiagenode: DNA methylation in biofluids: from genome-wide studies to targeted approaches<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<p><em><strong>Speaker: Matteo Tosolini, PhD<\/strong>, Business Development Manager, Epigenomic Services Profiling, Diagenode, a Hologic Company<\/em><\/p>\n\n\n\n<p>DNA methylation is an epigenetic mechanism characterized by the addition of a methyl group to the DNA, mainly at cytosines. It can occur at different genomic locations, and it can modify gene expression and function. The profile of DNA methylation is tissue-type and cell-type specific. A hallmark of cancer is the presence of an aberrant DNA methylation profile and this modification appears to happen early during carcinogenesis. For these reasons DNA methylation can be used as a cancer specific biomarker.<\/p>\n\n\n\n<p>Circulating cell-free DNA (cfDNA) is composed by fragmented DNA released by different mechanisms into the bloodstream, mainly from apoptotic cells including healthy body cells as well as cancer cells. Analysis of cfDNA is very promising and has a great potential in cancer diagnostics given its noninvasive approach requiring only a blood or plasma sample in a process known as liquid biopsy. Interestingly cfDNA retains the genetic and epigenetic information of the tissue of origin. Circulating tumour DNA (ctDNA), meaning DNA fragments that originate from cancer cells, can thus be used as potential biomarker for early cancer detection and diagnosis. The first proof of concept was published last year by the Circulating Cell-free Genome Atlas consortium (CCGA).<\/p>\n\n\n\n<p>The analysis of methylated cfDNA by bisulfite sequencing does not come without challenges as those samples are in low quantity and poor quality because cfDNA is highly fragmented and the ctDNA is diluted by cfDNA from normal body cells.<\/p>\n\n\n\n<p>In this webinar we will present how Diagenode can help by applying our workflow of DNA methylation biomarker discovery and validation in biofluids. We will start with Whole Genome Bisulfite Sequencing (WGBS) on cfDNA to determine the CpGs and the pattern of DNA methylation by using standard statistics as well as data mining approaches and to discriminate between different groups. We will proceed with the most adapted and fully customized Targeted Bisulfite Sequencing approach on cfDNA to validate the previously identified CpG methylation signature as biomarker and screen a higher number of patients.<\/p>\n\n<\/div>\n<\/details>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p><strong>13:00 \u2013 13:50<\/strong> <a href=\"https:\/\/dateful.com\/time-zone-converter?t=1114&amp;tz2=Berlin-Germany\" target=\"_blank\" rel=\"noreferrer noopener\">(Berlin \/ Germany)<\/a><\/p>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\nArima Genomics: 3D Genome Analysis Identifies Therapeutic Targets in Pediatric Brain Cancer<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<p><em><strong>Speaker: Anthony Schmitt, PhD.<\/strong>, SVP of Science, Arima Genomics<\/em><\/p>\n\n\n\n<p>Ependymoma is a tumor of the brain or spinal cord. The two most common and aggressive molecular groups of ependymoma occur mainly in young children and frequently recur after treatment.<\/p>\n\n\n\n<p>Although molecular mechanisms underlying these diseases have recently been uncovered, they remain difficult to target. Innovative therapeutic approaches are urgently needed.&nbsp;<\/p>\n\n\n\n<p>Join this webinar to learn how we:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Uncovered chromosomal rearrangements and regulatory mechanisms underlying aberrant expression of genes that are essential for ependymoma tumorigenesis.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Identified potential novel therapeutic vulnerabilities in ependymoma and validated newly identified therapeutic targets through genetic or pharmacologic inhibition experiments.&nbsp;<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Revealed tumor-dependency genes and pathways by oncogenic 3D genome conformations even in tumors that lack known genetic alterations.<\/li><\/ul>\n\n<\/div>\n<\/details>\n\n\n\n<details  class=\"vf-details\" id=\"\"  >\n<summary class=\"vf-details--summary\">\n Dovetail Genomics: Structural and functional heterogeneity in the spatial organization of glioblastoma patient genomes<\/summary>\n<div class=\"acf-innerblocks-container\">\n\n<p><em><strong>Speaker: Argyris Papantonis<\/strong>, Dovetail Genomics<\/em><\/p>\n\n\n\n<p>Recent work has established that 3D genome organization is causally linked to gene expression control, also in tumors and cancer. In addition, most cancer genomes are infested with structural variants (SVs) that contribute to oncogenesis and cancer progression via various mechanisms. We performed Hi-C experiments on glioblastoma stem cells (GSCs) from 26 patients to generate a resource of &gt;13 billion contacts. We used this Hi-C data resource to detect and characterize patient-specific SVs, and then build individualized genome references. &nbsp;We identified &gt;1100 high-confident SVs, which were highly heterogeneously distributed across the 26 patient genomes. Following integration with gene expression data, and despite heterogeneity, we found partially recurrent effects on gene expression misregulation that could be linked to the formation of many hundreds of neo-TADs and neo-loops in these GSC genomes. Together, this is the first such comprehensive approach in leveraging 3D genome heterogeneity to understand regulatory dependencies in glioblastoma.<\/p>\n\n<\/div>\n<\/details>\n<\/section>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<p><\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"parent":0,"menu_order":0,"template":"","embl_taxonomy":[],"class_list":["post-1209","vf_event","type-vf_event","status-publish","hentry"],"acf":[],"embl_taxonomy_terms":[],"vf_event_start_date":{"value":"20211122","formatted":"22 November 2021"},"vf_event_end_date":{"value":"20211124","formatted":"24 November 2021"},"vf_event_submission_opening":{"value":"","formatted":""},"vf_event_submission_closing":{"value":"20210928","formatted":"28 Sep 2021"},"vf_event_registration_opening":{"value":"","formatted":""},"vf_event_registration_closing":{"value":"20211115","formatted":"15 Nov 2021"},"vf_event_summary":{"value":"This conference will provide an opportunity to learn about and keep up to date with the rapidly progressing area of cancer genomics. 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